USP Labs Ultimate-T Review

Ultimate T is a test-booster by USP Labs. It contains just four primary active ingredients, two of which are well-established at this point, one of which is found in Pink Magic Platinum, and one of which we’ve never encountered before…

Ultimate T

Symplocos Racemosa

Symplocos Racemosa is a flowering plant (indigenous to parts of Asia) which has demonstrated PDE inhibiting properties in vitro.  PDE’s are a family of enzymes which are partially responsible for the degradation of cAMP, a signaling molecule involved in many physiological functions, one of them being hormone production.  In other words, increasing cAMP can increase Tesetosterone.

In the context of Ultiamate T, however, Symplocos Racemosa isn’t so much a test “booster” but may have a preservative effect on Testosterone.  The magnitude of such an effect remains unclear, as Symplocos Racemosa hasn’t been studied in humans with regards to Testosterone-boosting.

Withania Somnifera

Withania Somnifera, otherwise known as Ashwagandha, is an adaptogenic herb with an extremely wide variety of potential and known health benefits.  It is often used to decrease Cortisol levels, a benefit which is quite reliable, but has also been investigated as a test-booster in more than one study.

A 2010 study, published in Fertility and Sterility”, found that Ashwagandha (5g basic root powder) was able to restore Testosterone levels in infertile men, though subjects did not experience spikes beyond the normal range.

These findings were replicated in a 2011 study in which it was also noted that the effects were more apparent in stressed men (Ashwagandha is a known adaptogen).

In the context of Ultimate T, Ashwagandha may help optimize Testosterone, but any sort of massive increase is unlikely.  The lower your initial Testosterone levels, the more likely you are to experience a Testosterone increase, but this would be attributed to normalization, not an outright increase.

Spilanthes Acmella

Spilanthes Acmella first appeared in USP’s Pink Magic Platinum.

It has been shown to dose dependently increase Testosterone levels in mice, but this is currently the only in vivo study regarding the effect Spilanthes Acmella on Testosterone levels.

Once some human research has been published, we will be better able to understand the efficacy of this ingredient in the context of a test-booster like Ultimate-T, but until then we would still consider it pretty speculative (in terms of efficacy).

Eurycoma Longifolia

Eurycoma Longifolia, also known as Tongkat Ali has been shown, in various studies, to increase Testosterone in male rats, but the only human studies that exist have tested the effects of Eurycoma Longifolia in infertile men, not healthy men.

A 2010 study published in the “Asian Journal of Andrology” found that supplementation with 200mg of an extract of Eurycoma Longifolia significantly improved various indications of male fertility (in humans), though the mechanism of action was unknown.

A 2012 study published in “Andrologia: Volume 44” (the same researchers from the above mentioned human study) found that men suffering from Hypogonadism (diminishing functionality of the gonads) who were treated with a 200 mg daily dose of Eurycoma longifolia extract reached normal Testosterone levels after a 30 day period.

It’s unclear how much Eurycoma Longifolia is present in Ultimate T, but since it’s listed last in the proprietary blend we can be pretty sure it’s less than 100mg or so.

The Bottom Line

Ultimate T definitely has what it takes to encourage optimal Testosterone levels, but we can’t say any certaintly that it will noticeably increase Testosterone levels in healthy (normal Test testosterone) individuals.  Like most USP Labs products, it contains a mix of some well-established ingredients as well as some that are pretty speculative, so ultimately there is a “try and see” aspect to Ultimate T.

[expand title=”REFERENCES” tag=”h5″]

  1. Kiasalari, Zahra, Mohsen Khalili, and Mahbobeh Aghaei. “Effect of withania somnifera on levels of sex hormones in the diabetic male rats.” Iranian Journal of Reproductive Medicine 7.4 (2009): 163-168.
  2. Ahmad, Mohammad Kaleem, et al. “< i> Withania somnifera improves semen quality by regulating reproductive hormone levels and oxidative stress in seminal plasma of infertile males.” Fertility and sterility 94.3 (2010): 989-996.
  3. Mahdi, Abbas Ali, et al. “Withania somnifera improves semen quality in estress-related male fertility.” Evidence-Based Complementary and Alternative Medicine2011 (2011).
  4. Tambi, M. I. B. M., M. K. Imran, and R. R. Henkel. “Standardised water‐soluble extract of Eurycoma longifolia, Tongkat ali, as testosterone booster for managing men with late‐onset hypogonadism?.” Andrologia 44.s1 (2012): 226-230.
  5. Ang, H. H., S. Ikeda, and E. K. Gan. “Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack.” Phytotherapy Research 15.5 (2001): 435-436.
  6. Zanoli, P., et al. “Influence of< i> Eurycoma longifolia on the copulatory activity of sexually sluggish and impotent male rats.” Journal of ethnopharmacology 126.2 (2009): 308-313.
  7. Ang, H. H., S. Ikeda, and E. K. Gan. “Evaluation of the potency activity of aphrodisiac in Eurycoma longifolia Jack.” Phytotherapy Research 15.5 (2001): 435-436.
  8. Abbasi, Muhammad Athar, et al. “Phosphodiesterase and thymidine phosphorylase-inhibiting salirepin derivatives from Symplocos racemosa.”Planta medica 70.12 (2004): 1189-1194.
  9. Kumar, V. Prashanth, et al. “Search for antibacterial and antifungal agents from selected Indian medicinal plants.” Journal of Ethnopharmacology 107.2 (2006): 182-188.

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