PES GenoFlex Review

GenoFlex is a joint-support supplement by PES, the brand behind other highly rated supplements such as High Volume, which contains just three ingredients…

PES GenoFlex


Cissus Quadrangularis

Cissus Quadrangularis has become a relatively common ingredient in joint support formulas, so it’s not surprise that PES opted to include it in GenoFlex.

Cissus has been shown to reduce joint pain in exercising individuals and there is preliminary evidence indicating it also supports bone and connective tissue health.

A clinical dose of Cissus, for the purpose of reducing jont pain, is considered 3200mg per day, though the standardization of extracts may vary considerably.

While PES makes no mention of the standardization of the Cissus used in GenoFlex, the formula does contain a near-clinical 2900mg dose.

Passion Fruit Extract

If you like your exotic fruits, you’ve probably come across Passion Fruit before, but most people are likely unaware of the benefits Passion Fruit has to offer when it comes to joint support.

Passion Fruit extract has been shown to reduce joint stiffness and pain as well as improve joint functionality in human subjects with oseoarthritis.

Although we still need a bit more research before Passion Fruit can be considered effective and reliable in the eyes of science, the preliminary research is quite encouraging.  This makes Passion Fruit Extract a fine addition to the PES GenoFlex formula, not to mention helping to set it apart from various other joint support formulas on the market.

GenoFlex contains 150mg of Passion Fruit Extract, the same dose used in the study referenced above.

Boswellia Serrata

Boswellia Serrata is one of the most extensively-researched joint support supplements available, having demonstrated the ability to reduce inflammation and swelling associated with osteoarthritis in multiple human studies.

Of course, as with any plant extract, quality is important.  We usually recommend patented forms of Boswellia, such as 5-Loxin, which has been used clinically and proven to be quite effective.

GenoFlex contains 100mg of ApresFlex, another patented Boswellia extract, adding an element of certainty and trustworthiness that is generally lacking with joint support formulas that use no-name extracts.

Is GenoFlex Safe?

There is no evidence to suggest that any of the ingredients in GenoFlex are dangerous or harmful in any way.  In fact, they are all quite well-tolerated in human studies.

The Bottom Line

Although the formula is fairly simple, with only three key ingredients, PES GenoFlex definitely has what it takes to improve overall joint health and reduce pain/inflammation.  It makes sense for athletes who have joint problems or are concerned about developing joint problems, and the benefits will likely become more and more noticeable over time.

Still not sure which joint-support supplement is right for you?  Check out our Best Joint Support Supplements List! exists to educate the supplement community and seperate the science from the hype.

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