Naturo Nitro Decimus Pre-Workout Review

Naturo Nitro Decimus is a multi-faceted pre-workout supplement which is designed to increase strength and muscular endurance as well as enhance focus and energy…

Naturo Nitro Decimus Pre-Workout



Beta-Alanine is the rate limiting amino acid in the formation of Carnosine, a dipeptide (Beta-Alanine + Histidine) that can drastically reduce lactic acid build-up in muscle tissue, resulting in better musclular endurance. Beta-Alanine supplementation is an effective and reliable means of increasing muscle Carnosine levels, and this increase has been shown to improve muscular endurance in human subjects.

The clinical range for Beta-Alanine is roughly 3-6g, with daily doses as low as 1.6g being able to increase Carnosine, aleit at a slower rate. Naturo Nitro Decimus contains an undisclosed dose of Beta-Alanine, but given it is listed first in a 3000mg proprietary blend, 1.6g seems reasonable.

Arginine AKG

Arginine AKG is simply the amino acid Arginine bonded with Alpha-Ketoglutaric Acid and is generally touted as a more bioavailable form of Arginine. This is all sounds great, but Arginine AKG has actually failed to influence Nitric Oxide levels and blood-flow in one study, with no other studies proving any other benefits.

So, it would seem that Arginine AKG is more of a buzz ingredient. In the context of Naturo Nitro Decimus it’s a pretty useless ingredient.


Agmatine hasn’t been studied as extensively as Beta-Alanine or Arginine, but the preliminary research is quite promising. Agmatine has been found to increase Endothelial Nitric Oxide Synthase, the enzyme that catalyzes the production of Nitric Oxide. It has also been shown (in mice) to increase glucose uptake in muscle cells, a mechanism that may offer some addition performance enhancement.

At this time, however, Agmatine has not been studied in humans so it remains a “try and see” ingredient. Some people swear by it while others would rather see some hard data (in humans) before giving it a try. Effective doses range from 500-1500mg, with the dose in Naturo Nitro Decimus most likely falling towards the lower end of that range.

Creatine (Monohydrate, Magnesium Chelate, HCL)

Creatine is one of the most extensively-researched performance enhancing supplements, with all of the research indicating that it is quite effective when used consistently for several weeks. The benefits of Creatine include increased strength, fuller/bigger muscles, and enhanced recovery from exercise.

The clinical range for Creatine is 3-5g/day with doses as low as 2g falling short in terms of performance benefit.

Unfortunately, Naturo Nitro Decimus contains just 2g of total Creatine from three sources. Since neither Creatine HCL or Creatine Magnesium Chelate is more effective than Monohydrate, this is essentially like taking 2g of Monohydrate. Over the very long-term, users might notice some increases in strength and muscle-size, but ideally we’d like to see some more Creatine in there.

Caffeine Anhydrous

Caffeine is easily the most common ingredient in stim-based pre-workout supplements because it is a reliable and safe way of increasing perceived energy and enhancing focus during exercise and has some inherent performance enhancing qualities beyond just the mental aspect.

Naturo Nitro Decimus Pre-Workout contains an unknown amount of Caffeine, but we’d estimate somewhere around 200mg.

Guarana and Yerba Mate

Guarana and Yerba Mate are simply additional sources of Caffeine, and have not been shown to differ in any way from Caffeine Anhydrous in terms of energy-enhancing effects.


N-Methyltyramine (NMT) is capable of blocking the reuptake of Noradrenaline in the brain. By itself it’s nothing special, but NMT can enhance the effects of stimulants such as Caffeine because the Noradrenaline that Caffeine releases is not subject to reuptake (as much).

So far, no human studies have been conducted but in the context of Decimus, NMT is potentially quite effective for enhancing the overall focus/energy/mood aspect of the formula.


Picamilon is a combination of GABA and Niacin (Vitamin B3) which is said to be able to cross the blood brain barrier where it can fulfill the physiological functions of each of it’s components. However, there is absolutely no human research which has sought to determine whether Picamilon can aid in performance, just theories.

This is one ingredient that appears to have caught on for no reason at all. In the context of Decimus, Picamilon probably doesn’t do much.

Yohimbe HCL

Yohimbe is generally standardized for Yohimbine, an alpha-receptor antagonist which can increase the amount of fat burned during exercise and appears to be quite potent at doing so. While it doesn’t necessarily have any direct performance implications, it may just further enhance the stimulant aspect of Naturo Nitro Pre-Workout Octane and is ultimately the ingredient that leads us to classify the formula as “high stim”.

Yohimbine isn’t for everyone, so be careful with dosing. To learn more about the fat-burning benefits of Yohimbine, check out this article.


Like Picamilon, Dendrobium is one of those ingredients that caught on for reasons unknown. It was originally alleged to contain PEA and PEA metabolites, but this claim has since been refuted.

Ultimately, it probably doesn’t help the Naturo Nitro Decimus formula much, but probably doesn’t hurt much either.

The Bottom Line

Naturo Nitro Decimus Pre-Workout will give the average person a noticeable boost of energy and focus, but some of the performance enhancing ingredients may be a little under-dosed so increases in strength and endurance may not be particularly noticeable.

Still don’t know which pre-workout is right for you? Check out our Top 10 Pre-Workout Supplements list for some recommendations.


  1. Willoughby, Darryn S., et al. “Effects of 7 days of arginine-alpha-ketoglutarate supplementation on blood flow, plasma L-arginine, nitric oxide metabolites, and asymmetric dimethyl arginine after resistance exercise.” International Journal of Sport Nutrition andExercise Metabolism 21.4 (2011): 291.
  2. Sale, Craig, Bryan Saunders, and Roger C. Harris. “Effect of beta-alanine supplementation on muscle carnosine concentrations and exercise performance.” Amino acids 39.2 (2010): 321-333.
  3. Derave, Wim, et al. “β-Alanine supplementation augments muscle carnosine content and attenuates fatigue during repeated isokinetic contraction bouts in trained sprinters.” Journal of applied physiology 103.5 (2007): 1736-1743.
  4. Hobson, Ruth M., et al. “Effects of β-alanine supplementation on exercise performance: a meta-analysis.” Amino acids 43.1 (2012): 25-37.
  5. Morrissey, Jeremiah J., and Saulo Klahr. “Agmatine activation of nitric oxide synthase in endothelial cells.” Proceedings of the Association of American Physicians 109.1 (1997): 51-57.
  6. Chang, Chin-Hong, et al. “Activation of imidazoline I 2B receptors by guanidine to increase glucose uptake in skeletal muscle of rats.” Neuroscience letters467.2 (2009): 147-149.
  7. Kreider, Richard B., et al. “Effects of creatine supplementation on body composition, strength, and sprint performance.” Medicine and science in sports and exercise 30 (1998): 73-82.
  8. Volek, JEFF S., et al. “Performance and muscle fiber adaptations to creatine supplementation and heavy resistance training.” Medicine and science in sports and exercise 31 (1999): 1147-1156.
  9. Birch, R., D. Noble, and P. L. Greenhaff. “The influence of dietary creatine supplementation on performance during repeated bouts of maximal isokinetic cycling in man.” European journal of applied physiology and occupational physiology 69.3 (1994): 268-270.
  10. Thompson, C. H., et al. “Effect of creatine on aerobic and anaerobic metabolism in skeletal muscle in swimmers.” British journal of sports medicine30.3 (1996): 222-225.
  11. Costill, D. L., Gl P. Dalsky, and W. J. Fink. “Effects of caffeine ingestion on metabolism and exercise performance.” Medicine and science in sports 10.3 (1977): 155-158.
  12. Evans, Christine S., E. Arthur Bell, and E. Stewart Johnson. “N-methyltyramine, a biologically active amine in Acacia seeds.” Phytochemistry18.12 (1979): 2022-2023.
  13. Ostojic, Sergej M. “Yohimbine: the effects on body composition and exercise performance in soccer players.” Research in Sports Medicine 14.4 (2006): 289-299. exists to educate the supplement community and seperate the science from the hype.

Click to comment
To Top