Vindicate is a BCAA-based supplement by Dynamik Muscle which provides a standard array of intra-workout and recovery ingredients designed to promote muscle growth, reduce soreness, and generally improve aspects of recovery…
Luecine is the most potent amino acid when it comes to stimulating muscle protein synthesis (MPS). It stimulates MPS by activating mTOR, a signaling molecule that tells the body to initate muscle protein synthesis.
While most high protein diets already contain plenty of Leucine to ensure that MPS is optimized, Leucine may be especially useful for those who train in a fasted state or are on a calorie restricted diet (and getting less protein than they should). Leucine is capable of reducing muscle breakdown which generally occurs during fasted training, but without spiking Insulin levels and negating the accelerated fat-loss that occurs when Insulin levels are low
Most BCAA supplements under-dose Leucine, sometimes quite considerably. Vindicate contains 2.5g of Leucine per serving, not too under-dosed but not what could be considered a clinical dose either. Ideally, you should shoot for 3-5g of Leucine in your BCAA supplement to ensure the muscle growth promotinig results.
Isoleucine, like Leucine, is one of the three Branched Chain Amino Acids (BCAAs). Unlike Leucine, it doesn’t have particularly profound impact on muscle protein synthesis, but may encourage glucose uptake into muscle tissue which is generally viewed as beneficial for exercise.
Vindicate contains 1.25g of Isoleucine, not a particularly high dose but then again, Isoleucine isn’t actually that important of an ingreidents so it doesn’t really matter.
Valine is the third Branched Chain Amino Acid and also happens to be the least important, atleast in the eyes of science. It does not have a strong impact on MPS (like Leucine) nor does it induce glucose uptake into muscle tissue (like Isoleucine). There is some preliminary evidence to indicate that it may reduce fatigue by competing with Tryptophan for transport into the brain, but it seems more likely that all BCAA do this, not just Valine.
Still, it doesn’t hurt to include it, so in the context of Vindicate, Valine is a fine addition.
L-Carnitine L-Tartrate is a quickly absorbed form of Carnitine (bonded with Tartaric Acid) which has been the prefered form used in the studies which investigated the effects of Carnitine on aspects of recovery. Research confirms that L-Carnitine L-Tartrate is indeed an effective recovery aid, and can reduce biomarkers of oxidative damage to muscle tissue caused by exercise.
The clinical range is 1-2g, and since Vindicate provides 1g per serving, the formula will provide recovery benefits.
We discuss the recovery benefits of L-Carnitine L-Tartrate further in this article.
Glutamine became pretty popular in the early days of bodybuilding, mostly based on a lot of hype. It was alleged to provide a multitude of benefits, including muscle-building and perrformance enhancement, but research has disproved most of these benefits.
Glutamine may be useful for combatting exercise-induced immune suppression if you’re engaging in long-term exercise lasting more than a couple hours (like marathon running), but short-term resistance training does not deplete Glutamine levels.
We discuss Glutamine in-depth in this article.
Is Dynamik Muscle Vindicate Safe?
Vindicate is entirely safe. There is nothing in the formula that is inherently dangerous, even if you were to double the dose. This is mostly because it contains no stimulants, just some amino acids that can be found in whole proteins as well as naturally occuring inside your body.
The Bottom Line
Vindicate is pretty average as far as BCAA supplements are concerned. We would prefer to see more Leucine, more L-Carnitine L-Tartrate, and no Glutamine (because Glutamine is pretty much useless), but overall it’s not a bad formula. It certainly won’t make our Best Amino Acid Supplements list, but then again, it doesn’t seem like Dynamik Muscle was trying to shake things up with this one.