Clonazolam: An Insanely Powerful Designer Benzo

hand full of clonazolam pills

Clonazolam is part of a recent wave of so-called ‘designer benzodiazepines’.

These substances function much like ordinary prescription benzos, but for one reason or another, they never became approved drugs.

Instead, they occupy a kind of legal gray area where unapproved, unscheduled drugs can be legally sold as research chemicals.  Several designer benzos have come on the scene in recent years but  trust me when I say…

Clonazolam is no ordinary benzo!

It is extremely powerful–even at very low doses–and there is very little research on it at all, so people are just kind of making it up as they go along.

In terms of the pharmacological effects, Clonazolam is similar to other benzodiazepines, but if you read user experiences, you’ll find an abnormally high amount of black-outs, severe memory loss, and of course, the occasional car accident.

For better or for worse, Clonazolam is making quite a splash!

So what’s the deal with this stuff?!

Why is it so powerful?

Is it safe?

How is it legal?!

Don’t worry, we’ll answer all those questions and more in this article and I’ll also share my personal experience as well.

By the end, you’ll know everything there is to know about Clonazolam.

Once you’re up to speed, you can make up your own mind about whether it’s worth it or not.

Let’s get started…

What Is Clonazolam?

Clonazolam is a designer benzodiazepine which has gained much recognition in the last couple of years as a research chemical and recreational drug, similar to Etizolam.

Clonazolam Molecule

It was first synthesized in the early 1970’s by researchers at The Upjohn Company.  Patents were filed shortly after, but Clonazolam never even became a drug candidate, let alone an approved drug.

It’s not exactly clear why Clonazolam was abandoned, but it likely had to do with the fact that Alprazolam (Xanax) was invented just a few years later by the same pharmaceutical company (Upjohn).

Upjohn is part of Pfizer now, but it wasn’t such a massive company back then.  One company with limited resources can only pursue so many drug approvals.

Ultimately, it seems as though the decision to invest resources and attention in Xanax instead was a fruitful one, since it’s now one of the most widely used (and abused) drugs of all time.

Clonazolam faded into obscurity for a few decades but, thanks to the rise of internet-based research chemical vendors, it’s making a comeback.

Users typically liken the effects of Clonazolam to traditional benzos like Clonazepam and Xanax, but with a stronger degree of sedation and amnesia.

Just google around a bit and you’ll read reports of Clonazolam users blacking out, passing out, and not remembering a thing!

As it turns out, some people like that.

What Are The Effects Of Clonazolam?

Like all benzodiazepines, Clonazolam slows down Central Nervous System (CNS) activity and produces depressant effects.

Anecdotal reports indicate that it produces much more in the way of sedation and amnesia than benzos of similar potency like Xanax or Etizolam.

On average, the direct effects of Clonazolam are:

  • reduced anxiety
  • muscle relaxation
  • lowered inhibitions
  • sedation
  • impaired physical abilities

You may recognize these effects as basically the same as every other benzo–and that’s true–but due to the unique pharmacological activity of Clonazolam, the effects differ from other benzos.

How Does Clonazolam Work?

Clonazolam is a benzodiazepine, so it works in more or less the same way as the rest of the chemicals in the class:

By interacting with a specific subset of GABA-A receptors (benzodiazepine receptors) in the brain and ultimately increasing the activity of the neurotransmitter, GABA.

GABA is the chief inhibitory neurotransmitter in the Central Nervous System (CNS).  It’s job is simply to reduce the firing of neurons (nerve cells) which slows down brain activity.

At its core, anxiety is the result of an overactive brain so increasing GABA activity (and therefore reducing brain activity) tends to have an anxiolytic (anxiety-reducing) effect.

That’s why pretty much all anti-anxiety drugs target GABA receptors on some level.

There are 5 sub-units of GABA-A receptors and the precise effects of benzodiazepines vary depending on which sub-units they have a higher affinity for.

For example, benzos that bind to GABA-A sub-units 1 and 5 typically produce more sedation and amnesia, whereas benzos that bind to sub-units 2 and 3 of the GABA-A receptor tend be more anxiolytic.

Of course most benzodiazepine drugs bind to multiple GABA-A sub-unit receptors, to different extents, so predicting the effects of any particular benzo is far from an exact science.

Still, understanding the basic pharmacology underlying the effects of these substances can help us understand which ones are useful in certain instances.

Unfortunately, not much is known about the pharmacological mechanisms of Clonazolam, other than that it functions like any other benzo.

Based on the fact that Clonazolam is very strong in terms of sedation and prone to causing amnesia, it likely has a high affinity for GABA-A1 receptors and/or GABA-A5 receptors.

That’s pure speculation though.

The truth is, we know nothing about the precise mechanisms underlying the effects other than that Clonazolam is a benzodiazepine which works the same as any other benzo.

Is There Any Actual Research On Clonazolam?

Not really.

In contrast to other research chemicals like Etizolam, which is a prescription drug in some countries, Clonazolam has no accepted medical use.

Since it’s not a prescription drug and never was one, it’s never been studied in a living organism.

This was a compound which was discovered/invented more or less by accident, as part of a larger initiative to come up with marketable benzodiazepines in the 1970’s and 80’s.

It doesn’t look like Clonazolam was ever paid much attention or taken seriously as a potential drug candidate.

All we really have in the way of ‘research’ is a general mechanism of action based on the fact that we know Clonazolam is a benzodiazepine and we know how benzodiazepines work.

Other than that, most of what is known about Clonazolam comes from user experiences which, although highly subjective and often heavily biased, seem to follow a common theme.

Clonazolam is quite sedating and likely to cause amnesia, even at low doses.

Clonazolam Dosage

Since Clonazolam was abandoned as a drug candidate and with it, all future research attempts.

This makes it difficult to determine a ‘clinically effective dosage’, but based on anecdotal evidence, an effective dosage of Clonazolam is as little as 0.5mg.

Most users start at 0.5-1mg, but some people have reported taking much higher doses.

I’ll discuss my personal experience with Clonazolam shortly, along with the dosages I was taking, but first, let’s talk side effects.

Clonazolam Side Effects

Like any benzo, Clonazolam comes with it’s fair share of potential side effects

The most common side effect reported with Clonazolam are:

  • dizziness
  • headaches
  • loss of motor control
  • amnesia (blacking out and not remembering anything)
  • heavy sedation (more than you might prefer)
  • respiratory depression
  • rebound anxiety (when you withdraw)

As with any drug–and this is especially true for benzodiazepines–the side effects can range from minimal to severe.

Some users may experience nothing negative while others may have a horrible experience.

Your experience is going to depend on a lot of underlying factors, including your personal tolerance to benzodiazepines as well as individual differences in brain chemistry.

As with any drug, increasing the dosage increases the likelihood of side effects, so starting with a low dose would be wise for first-time users.

Liquid, Powder, or Pellets (Tablets)?

The first thing you’re most likely going to notice when purchasing Clonazolam is that different vendors offer it in different forms.  It’s not exactly clear why they do this, but you’ll find Clonazolam as either a:

  • Powder
  • Pellet (Tablet)
  • Liquid (mg/ml)

Although technically, all of these are suitable, I personally prefer pre-dosed pellets.

My issue with powders is that you’re dealing with extremely small amounts (.05mgs) so unless you have a precision .000 scale, your basically screwed.

As for liquids, I just try to stay away from them because they’re messy, often not packaged well, and sometimes they contain materials that degrade the active.

Me, I’m a tablet kinda guy for sure.

My Personal Experience With Clonazolam

I first became aware of Clonazolam actually somewhat recently, after doing some in-depth research for my article on Etizolam and visiting the websites of several research chemical vendors.

After reading a bunch of reviews from people raving about how powerful this stuff is, I decided to give it a whirl.

I have extensive experience taking benzodiazepines.  Xanax, Klonopin, Temazepam, Valium, Lorazepam.  All the major players.

So I didn’t expect Clonazolam to be anything special.  Man, was I wrong…

I popped 1mg and about a half hour later I felt extremely loose, uninhibited, and mildly euphoric, like I took 2mg of Xanax or Klonopin.

About a half hour after that, a powerful level of sedation came over me–more powerful than any prescription benzo I’ve ever taken–and I ended up passing out for several hours.

I woke up with no recollection of the events that had transpired, other than what I just told you.

There was one more experience that’s probably worth discussing because it speaks to the potency of the drug more so than any of my previous experiences.

I was wired on a high dose of Focalin and needed to get some sleep.  If you’ve ever used Focalin (or Adderall) or anything like that, you know how impossible the proposition of sleep seems while your on it.

So, I decided to take my last two Clonazolam pellets (2mg total) at once.  I figured 1mg to bring me back down and 1mg to put me to sleep.

Sound logic…NOT!

About 30 minutes after I took my Clonazolam I was out like a light. There was no middle-ground.  No high or even a leveling out of any kind.

I woke up feeling mildly groggy and not really remembering what happened other than that.

One minute I was wired and sleep wasn’t even an option.  They next minute I was waking up 8 hours later.

Overall, my experience with Clonazolam is similar to so many other experiences I’ve read online.  A benzo-like high followed by intense sedation and serious amnesia.

All benzos carry some risk of memory loss, but Clonazolam is particularly powerful in this regard.

Personally, I like Etizolam better.  I can actually function on it.  I’ve never found it to be particularly overwhelming.

Sad to say that all Clonazolam does it make me pass out or black out (or both) within about an hour of taking it.

Very useful if your trying to sleep but not particularly useful if you’re doing anything else.

Is Clonazolam Legal?

The legal status of Clonazolam is a little complicated…

Clonazolam is a ‘designer benzodiazepine’ which means it occupies a legal gray area where it is not an approved (prescription) medication, but is not illegal to possess, buy, or sell.

The DEA designates Clonazolam as part of a group of uncontrolled benzodiazepines along with:

  • flubromazolam
  • diclazepam
  • pyrazolam

And several other drugs as well.

These drugs are not controlled substances which means they are technically legal to buy and sell, just not for the purposes of human consumption.

Obviously, everyone that’s buying these chemicals is consuming them, but it’s just a legal loophole that exists until they get scheduled at the federal level.

Of course, individual states can also schedule substances, effectively making them controlled substances within that state.

The DEA also possesses the power to ’emergency schedule’ any substance which it deems to be dangerous enough, but so far, it has not done so with any designer benzos.

In the US, for whatever reason, the government seems more concerned with things like Kratom and Cannabidiol.

In Canada, Clonazolam is Schedule IV.

In the UK, it falls under the Psychoactive Substances Act.

Australia considers it a Schedule IV analogue.

Will Clonazolam Show Up On A Drug Test?

It depends entirely on what kind of test is being used.

Very few tests will test for Clonazolam specifically, but there’s always the possibility that, because it is a benzodiazepine, that it will come up positive for benzos in general.

The good news–if you’re about to get drug tested–is that Clonazolam has a short half-life so it won’t stick around your system as long as other benzos.

This isn’t going to sound cliche, but hear me out…

The best way to ensure you don’t fail a drug test is to not use drugs.

As someone that spent the better part of his teen years in and out of drug programs before ultimately realizing the quickest way out was just to stop doing drugs, I strongly encourage you to heed my advice.

Where To Buy Clonazolam

Clonazolam used to be more widely available on various research chemical websites but it seems to be pretty rare these days.  Unfortunately, the reputable site I’m aware of that you can buy Clonazolam from is:

You can also check out this article on Where To Buy Clonazolam for some additional vendors.

Just keep in mind…

Unlike Etizolam, which has become a very popular research chemical as of late, Clonazolam is not produced by any pharmaceutical companies.

Any Clonazolam you get is going to be produced by some sort of under-ground (mildly sketchy) research chemical manufacturer.

Most of these guys aren’t testing the finished product, so the amount of actual Clonazolam can often differ significantly from the stated amount.

In fact, considering Clonazolam is cheap to produce, it wouldn’t surprise me if many vendors were intentionally over-dosing.

As with any research chemical, it’s probably wise to buy the minimum amount of Clonazolam, confirm it’s legit, then consider buying more if you want.

There are A LOT of scam artists out there.   You’ve been warned!

The Bottom Line On Clonazolam

Clonazolam is a very powerful depressant and sedative of the benzodiazepine class.

It works similarly to other benzodiazepines, by increasing GABA levels and reducing overall brain activity, but it has a rather unique effect profile, compared to other benzos.

Even at low doses, Clonazolam is quite potent, causing many users to pass out and not remember what happened.

If that sounds like your cup of tea, go for it!

Personally, I’ll stick with Etizolam and Diclazepam–or maybe just a nice Indica/Sativa blend–which I find to have all the good qualities of of Clonazolam, but without the extreme sedation and memory loss.

To each his (or her) own though.  Just be careful…

Got Anything To Add About Clonazolam?  Any Experiences You’d Like To Share?  Comment Below…

I’m Matt Theis, founder of SuppWithThat, Momentum Nutrition, and Singular Sport. I created SWT to separate the science from the hype and publish accurate, research-based information on supplements. If you like what I have to say here, feel free to check out my supplements at and

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