The Ultimate Guide To Cannabidiol (CBD)

marijuana plants

If you want to know what Cannabidiol (CBD) is and all the unique health benefits it has to offer, then you want to read this article.

Medicinal Marijuana is nothing new.

It’s been used for thousands of years, by many different cultures, to treat a variety of ailments.

Unfortunately, due to it being banned at the federal level for nearly a century, there hasn’t been much scientific research to confirm many of the alleged benefits…

That is, until now!

The recent legalization of Marijuana in certain states like California, Colorado, and Washington has opened up the opportunity for researchers to study it on a broader scale than ever before.

This has lead to the discovery of all kinds of potential health benefits as well as a more thorough understanding of the individual active components of the plant, cannabinoids, and how they work.

THC is the most well-known of the cannabinoids because it’s primarily responsible for the high you get from smoking weed, but there are others…

Cannabidiol, also known as CBD, is the primary non-psychoactive component of Marijuana.

CBD doesn’t get you high like THC does, but research has confirmed that it has numerous health benefits.  In fact, many of the benefits of Marijuana in general can be attributed, at least in part, to Cannabidiol (CBD).

Thus, CBD oil has become one of the hottest natural products to hit the virtual shelves in years, used by millions of people for a myriad of purposes.

In this article, we’re going to dive deep into the world of Cannabidiol and CBD oil.  We’ll talk about what it is, where it comes from, and most importantly, how it can benefit you.

We’ll also discuss things like dosage, legality, and where to buy high quality CBD oil you can actually trust.

And, of course, I’ll share my personal experience with CBD oil as well.

By the end of this article, you’ll have a thorough, well-rounded understanding of what this unique natural substance is truly capable of and whether it can benefit you.

Let’s begin…

What Is Cannabidiol (CBD) Oil?

cannabis plant and cbd oil in jar

Cannabidiol, often abbreviated to CBD, is a type of cannabinoid found in Marijuana.

It’s pretty similar to THC in terms of chemical structure but, unlike THC, Cannabidiol is non-psychoactive.

thc molecule compared to cbd molecule

CBD oil is concentrated Cannabidiol which is typically produced from low-THC, high-CBD Marijuana strains, whereas medical Marijuana is typically optimized for THC content.

While Cannabidiol oil doesn’t produce psychoactive (high) effects like THC, it has many legitimate therapeutic and medicinal uses.

Given the destructive nature of many pharmaceutical drugs, the demand for natural alternatives has never been higher and CBD appears to be useful for treating a wide array of ailments.

Why Do People Use Cannabidiol (CBD) Oil?

People use Cannabidiol oil for variety of reasons.  Some of the most common  are:

  • chronic pain
  • stress and anxiety
  • inflammation
  • epilepsy
  • substance addiction
  • cancer

Of course, these are just a few of the main uses.  There are potentially a lot more…

The reality is, we’re still in the process of uncovering all the benefits CBD has to offer.  Different people use CBD oil for different reasons and new reasons keep turning up!

What Are The Benefits of Cannabidiol/CBD Oil?

Doctor explaining the health benefits of cannabidiol oil

Research on the health benefits of Cannabidiol dates back to the 1960’s, but in the last few years, scientific exploration has really exploded.

As I said earlier, we’re still in the process of understanding what kind of health benefits CBD is capable of providing, but so far, numerous benefits have been identified.

Some of them hold more scientific weight than others, but again, research is ongoing…

CBD Oil Reduces Stress And Anxiety

One of the central focuses of Cannabidiol (CBD) research has been its impact on anxiety and stress disorders.

CBD has been shown to reduce anxiety and stress, not just in animal models, but in actual people as well.

Research clearly shows that CBD oil can reduce anxiety in many different types of situations, from public speaking to post traumatic stress disorder (PTSD).

A comprehensive review, which compiled and interpreted data collected from multiple other studies found that, while more research is definitely needed, Cannabidiol (CBD) has “considerable potentional as a treatment for multiple anxiety disorders”.

CBD oil seems to have a decent amount of support from the psychiatric community.

This likely has to do with the fact that many anti-anxiety medications can be highly addictive and have some pretty nasty side effects.

Most healthcare professionals would prefer to prescribe something that’s all-natural and non-addictive, assuming equal efficacy.

CBD Oil Reduces Pain And Inflammation

Another key area of interest with Cannabidiol is pain management.  Marijuana, which contains CBD along with several other cannabinoids, has long been used for it’s analgesic (pain-reducing) properties.

So, it makes perfect sense that researchers trying to find ways of dealing with pain caused by various diseases and conditions would take an interest.

Topical CBD oil (applied on the skin where the pain is) has been shown to reduce pain and inflammation associated with arthritis, without side effects.

Research confirms that CBD oil reduces neuropathic pain as well, so the effects aren’t merely a result of reducing inflammation, as many other drugs and supplements have been shown to do.

In fact, CBD oil (or spray) has succeeded in reducing pain where other medications have failed.

How exactly Cannabidiol works to reduce pain and inflammation remains somewhat unclear, but the fact that it does work can no longer be denied.

CBD Oil Is An Anti-Psychotic

Many anti-psychotic medications come with a handful of side effects, some of which can be quite severe.  As you can imagine, the search for natural alternatives is ongoing.

One such natural alternative is CBD oil.

Cannabidiol has been shown to exert anti-psychotic effects in animals (mice and monkeys) and is now being investigated in humans.

Research shows that CBD is beneficial for both experimentally-induced psychosis and schizophrenia.

Although researchers are still searching for a precise mechanism of action, it looks like Cannabidiol works by increasing anandamide signaling.

Anandamide is an endocannabinoid (a fatty acid based neurotransmitter which binds to cannabinoid receptors).

Higher levels of anandamide are inversely correlated with symptoms of psychosis, so increases anandamide activity in the brain is generally seen as beneficial for treating psychotic conditions.

CBD Oil Has Anti-Cancer Properties

You may have heard from your hippy stoner friend that “weed cures cancer man”, and while this is definitely an absurd thing to say, it is absolutely true that weed has anti-cancer properties.

A fair amount of research has actually been conducted in this area, just not so much in humans.

Several cannabinoids, including CBD, have been shown to decrease tumor growth (in animals).  Since human studies are lacking, it’s tough to say whether CBD oil is really an effective cancer treatment.

Still, there are a ton of anecdotal reports of cancer patients using cannabinoids with favorable results.

While other cannabinoids found in Marijuana may be effective as well, Cannabidiol (CBD) appears to be especially effective, having been shown to reduce cancer cell proliferation and induce apoptosis (cell death) to a greater degree than Cannabis Sativa extract.

As with most of the medical uses for CBD oil, it’s not clear how exactly it fights cancer, but research suggests it has something to do with preventing angiogenesis.

Angiogenesis is the process by which new blood vessels are formed (from existing blood vessels).

These new blood vessels feed tumors which helps the cancer cells spread to surrounding tissues.  Blocking angiogenesis is one way to stop the spread of cancer.

So, does weed cure cancer?  Of course not.  That makes for a very clickable Facebook headline, but it’s not an accurate way to describe the relationship between CBD and cancer.

CBD does appear to be effective for stopping cancer from spreading, though.

Human studies are likely underway, but there are a TON of cancer patients who use CBD oil already for this very reason.

CBD Oil Helps Treat Epilepsy

Cannabis has been known to have anti-convulsant properties for a while, so it makes sense that Cannabidiol (CBD) has been clinically investigated as a potential treatment for epilepsy.

Regular use of CBD has been shown to reduce seizure frequency in people with treatment-resistant epilepsy.

In other words, it has succeeded where common anti-convulsant drugs have failed.

A year or two ago, there was some doubt as to whether Cannabidiol could really help prevent/reduce seizures, but at this point, multiple studies have demonstrated anti-convulsant benefits in human subjects.

So there’s really no doubt about it…

CBD definitely helps prevent seizures and has a better safety profile than other commonly prescribed treatments.


Research indicates it works by activating Cannabinoid (CB1) receptors, a well-established mechanism for preventing and/or reducing seizures.

If you or someone you know has epileptic seizures, it makes sense to consider CBD oil as a treatment option.  It’s just as effective as other anti-seizure drugs and potentially much safer.

CBD Oil May Help Manage Diabetes

CBD has been shown to decrease the incidence of Diabetes in lab mice, but it hasn’t been studied very extensively in humans yet.

One study found that, if anything, THCV–another nonpsychoactive cannabinoid found in Marijuana–was the more effective of the two at treating Diabetes (Type 2).

Cannabidiol definitely appears to have anti-diabetic properties, but to say that CBD oil is definitely an effective treatment for diabetes would be a bit of a stretch.

The good news is that with the legalization wave happening across the US right now, it’s much easier for all kinds of researchers to study the health benefits of Marijuana.

Considering roughly 10% of the population of the US has Diabetes, it’s a safe bet that a large chunk of the research will focus the Diabetes angle of cannabinoids in general.

So, while the current body of research doesn’t warrant us labeling CBD oil as an effective means of treating of managing Diabetes just yet, it won’t be long until we know for sure what it’s truly capable of.

CBD Oil Promotes Cardiovascular Health

In addition to have anti-diabetic properties, research research indicates that Cannabidiol is beneficial for cardiovascular health in general.

CBD has been shown to reduce blood pressure and normalize heart rate response in the presence of acute stress.

While not much is known about how CBD improves cardiovascular health, at least part of the benefits can be attributed to it’s ability to relax blood vessels to allow for optimal blood flow to and from the heart.

Like the anti-diabetic effects of CBD, the cardiovascular effects require much more elucidation, but the preliminary evidence seems to suggest it’s beneficial.

CBD Oil Reduces Nausea

Marijuana has long been recognized as an effective way to deal with nausea..

One of the reasons many cancer patients undergoing chemotherapy use Marijuana is because it helps counteract the nausea-inucing effects of the chemo drugs.

Research indicates that CBD is responsible for much of these effects, though other cannibinoids (including THC) reduce nausea as well.

Cannabidiol appear to exert it’s anti-nausea effects by activating 5-HT1(A) receptors, a subset of Serotonin receptors, activation of which is known to be inversely correlated with nausea.

Whatever the reason, nausea can be at least partially reduced by CBD oil, but some people may respond better than others.

CBD Oil Helps Treat Depression

Due to CBD increasing the activity of Serotonin receptors, it makes sense that it would be looked at as a potential treatment for depression.

Anti-depressant effects have been observed throughout multiple studies in animals, but human research is currently in short supply.

In the past, some people (weed haters) have asserted that Marijuana may actually lead to depression but, at this point, multiple studies have confirmed that’s not the case.

The endocannabinoid system does appear to play a role in depression, so it’s quite possible that CBD oil helps with depression, but further research is required to elucidate.

CBD Oil May Help With Addiction

Cannabidiol has also been looked at for treating addictive behavior.

Medical CBD is being developed for treating opiod addiction and a system review on the subject, which compared data from 14 different studies, concluded that CBD can potentially be useful for just about any substance addiction, from cocaine to tobacco to marijuana itself.

With substance addiction steadily on the rise in the US (and other countries too, I guess), there’s definitely a high demand for safe, effective treatment options.

While more research is certainly needed, the preliminary evidence definitely supports the notion that CBD oil can help treat addiction.

CBD Oil Supports Skin Health

A lot of people say that CBD Oil is beneficial for skin health, and there is some research to back that up.

Cannabidiol has general anti-inflammatory properties which are likely responsible for the skin health-related benefits.

In mice, CBD oil has been shown to be well-absorbed through the skin and topical creams have been developed using it as a key ingredient.

CBD Oil May Counteract The Negative Aspects Of THC

Although Marijuana is typically viewed as a pretty harmless drug, especially compared to ‘hard drug’ like cocaine and heroin, the truth is some users can suffer negative side effects.

  • impaired cognitive function
  • anxiety
  • paranoia
  • increased risk for addiction

It appears as though THC is responsible for a lot of these side effects, since CBD is remarkably harmless.

In fact, there is even some evidence to suggest that CBD can help counteract some of the negative side effects caused by THC.

Cannabidiol (CBD) Dosage

cannabidiol measuring utensil and CBD capsules

Studies have used a wide range of different doses of Cannabidiol, from 10mg to 1500mg.

How much CBD you need depends on what your using it for, though.

The anti-inflammatory, anti-diabetic, and cardiovascular benefits can be acheived at relatively low doses of 10-100mg.

The anxiety-reducing, anti-psychotic, and anti-convulsant benefits appear to require higher doses in the 150-600mg range.

Fortunately, research shows that CBD is remarkably safe, even at high doses (like 1500mg).

I personally recommend taking 30mg/day or so, just for general health purposes, but if you’re using CBD oil for certain medicinal purposes, you may have to take more than that.

Does CBD Oil Have Any Side Effects?

Cannabidiol oil has been well tolerated throughout every study, with only a few scattered reports of minimal side effects like:

  • tiredness
  • dry mouth
  • appetite increase

But these are rare.

By and large, CBD is extremely safe and unlikely to cause any adverse effects.

Even when combined with fentanyl–an insanely powerful opiod–CBD doesn’t exacerbate side effects.

That doesn’t mean you should mix it with a ton of other substances, though, because you never know how two substances will interact, but it does speak to the safety profile of CBD oil.

It’s pretty safe.

My Personal Experience With CBD Oil

I have plenty of experience with both THC and Cannabidiol, not to mention the other 80 or so cannabinoids which are naturally occurring in Marijuana.

Over the years, as more and more research has been published, I’ve become increasingly fascinated with CBD.

I’ve also purchased quite a few CBD oil products and used those as well, both in combination with Marijuana and in periods where I wasn’t using Marijuana.

CBD oil causes me to:

  • sleep better
  • eat more
  • have less joint pain

If you smoke or have smoked Marijuana, then you may recognize some of these benefits.

After all, most Marijuana strains contain both CBD and THC, even if they’re maximized for THC over CBD.

So, what’s the difference?

CBD provides some of the physical effects of smoking weed, but none of the psychoactive effects.

This makes it of interest to people who would use Marijuana, but can’t because they just don’t react well to the mental effects of it or don’t like it for whatever reason.

Personally, I like my THC, but CBD is great too.

Is CBD Oil Legal?

This is where it gets a little confusing…

According to companies that sell CBD oil and other Cannabidiol-based product, it’s legal.

According to the DEA, it’s not that simple.

At the federal level, Marijuana is a Schedule I substance, right up there with Heroin, Cocaine, and Methamphetamine, and several levels above drugs like Alprazolam (Xanax).

The Schedule I category is reserved for substances which have no medical use and have a high potential for abuse.

Now, obviously Marijuana is nowhere near as harmful or addictive as these other substances and it absolutely DOES have legitimate medical uses.

These laws are basically left over from an earlier time, when the US government was downright terrified of all psychoactive drugs and lumped Marijuana in with the others.

Since then, several states have passed legislation which makes Marijuana, and therfore CBD oil, legal to possess, buy, sell (with a license), etc.)

However, in many states, CBD oil could still be viewed as an illicit substance and could carry the same legal ramifications as marijuana use/possession/distribution/etc.

Here’s the thing:

It’s very unlikely that the DEA will start conducting raids on manufacturers of CBD oil products.

But the claim that CBD oil is 100% legal everywhere in the United States is false.

Nobody really knows exactly what the future holds for CBD oil.  As a consumer, though, your not taking much of a legal risk by seeking out and using CBD oil products.

If anything, the manufacturers of these products who distribute them via the internet to all 50 states are at risk.

Does Cannabidiol (CBD) Get You High?

No, CBD is non-psychoactive.

That means it doesn’t get you high, like THC.

The health benefits of CBD oil are physical, not psychotropic.

If you’re expecting some sort of high from CBD oil, you’re in for a disappointment.  If you do get some sort of high from CBD oil, it probably has THC in it too…

Will CBD Oil Make You Fail A Drug Test?

One of the primary concerns people have about using CBD oil (or any kind of CBD products) is that they might test positive for Marijuana on a drug test.

While it is true that there are tests to detect Cannabidiol, most drug tests–like the ones jobs and probation departments use–only test for the presence of THC.

THC is distinct enough from other cannabinoids like CBD that they’re unlikely to trigger false positives.

It’s more a matter of quality, though…

A high quality, pure CBD product is unlikely to trigger a false positive, but as you’re probably aware, not all CBD products are created equal.

Where To Buy CBD Oil

There are a ton of online vendors selling CBD oil, but only a handful of them provide quality products.  Unfortunately, it’s really hard to tell which vendors you can trust and which ones you should probably avoid.

Some vendors to consider are:

There are other brands, producers, and suppliers out there, but these are the two that I’ve actually ordered from and which I’m sure provide a quality product.

CBD oil tends to vary pretty considerably in price.  The quality products are typically more expensive, but you can’t necessarily equate price with value.

There are plenty of low quality, overly-expensive CBD oil products out there.

Do your research and choose wisely!

The Bottom Line On CBD Oil

a vile of cbd oil with marijuana

CBD oil products may be useful for treating a wide range of ailments and offer some unique general health benefits as well.

Unfortunately, science hasn’t caught up to many of the claims made about CBD oil.

We know it’s definitely useful for:

  • reducing anxiety
  • treating epilepsy
  • lessening pain and inflammation
  • managing certain neurological disorders

And it has general anti-cancer properties that are pretty interesting as well.

Still, the research on CBD is literally just starting.

With country-wide legalization of Marijuana on the horizon, it’s going to be easier and easier for researchers to study the benefits of Cannabidiol and other cannabinoids, not to mention less risky for companies to invest in.

When it comes to the benefits that medicinal Marijuana and CBD-based products have to offer, we may just be looking at the tip of the iceberg.

Got Anything To Add About CBD Oil?  Any Experiences You’d Like To Share?  Comment Below…

I’m Matt Theis, founder of SuppWithThat, Momentum Nutrition, and Singular Sport. I created SWT to separate the science from the hype and publish accurate, research-based information on supplements. If you like what I have to say here, feel free to check out my supplements at and

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