Tropinol XP is a test-booster by iForce Nutrition which contains some speculative, but potentially effective ingredients that we haven’t seen in many test-boosters before…FIND IT HERE
Fadogia agrestis is an African shrub which has historically been used as an aphrodisiac and pro-erectile agent in certain sects of traditional medicine. A 2005 study, published in the “Asian Journal of Andrology”, found that rats given Fadogia agrestis extract at oral doses of 18, 50, and 100mg/kg daily experienced dose-dependent increases in Testosterone, with the highest dose increasing achieving a roughly 6-fold increase by day 5 of treatment. Despite the notable increase observed in this study, the effect of Fadogia agrestis on Testosterone has not been studied in human subjects.
Given that this study used mice and has never been replicated in humans, the results are far from conclusive, though they are very encouraging. If these effects do translate to humans, Fadogia agrestis may be an effective way to boost Testosterone quickly and noticeably.
25R-DIONE SPIROST-4-ENE, 6 DIONE
25R-Dione Spirost-4-Ene, 6-Dione is a non-hormonal sapogenin which is alleged to increase lean mass though non-hormonal mechanisms. However, it remains extremely under-researched, despite a nearly 40 year old study demonstrating some efficacy in rats.
In 1975 study (yes, that long ago), Russian scientists reported that 25R-Dione Spirost-4-Ene, 6-Dione was able to induce anabolic changes (weight gain) in rats without effecting androgenic signaling (no influence on Testosterone).
The results of this study have never been replicated in rats or humans, so the potential of 25R-Dione Spirost-4-Ene, 6-Dione for increasing lean mass in humans remains very unclear. Due to the lack of research, we’d consider this a speculative ingredient for now which may or may not contribute to the overall anabolic effect of Tropinol XP.
Potassium Nitrate is a salt formed by a combination of Potassium and Nitrate ions. Though commonly used in industrial products and fertilizers, it’s safe to assume that, in the context of Tropinol XP, it serves as a Nitrate source. Nitrate, once inside the body, converts to Nitric Oxide and supplementation is associated with performance enhancement.
A 2012 study, published in “Journal of the Academy of Nutrition and Dietetics”, found that increased dietary nitrate intake (usually in the form of Nitrate-rich whole Beetroot) improved running performance in healthy adults. A 2013 study, published in the “European Journal of Applied Physiology”, found that Nitrate supplementation (from beetroot juice) effectively elevated plasma Nitrate levels which translated to improved performance during high-intensity exercise in athletes. A 2013 Meta-Analysis, which looked specifically at 17 separate studies using doses of 300-600mg Nitrate from various sources, concluded that supplementation is associated with a moderate improvement in time to exhaustion at a given work load.
Normally, supplemental Nitrate is found in the form of Beet Root Extract because Beets are naturally high in Nitrates. However, iForce has opted for an entirely different delivery route in the Tropinol XP formula by using Potassium Nitrate. While the dose of Potassium Nitrate in one serving may be relatively low, consuming 4 servings of Tropinol XP (as directed) will most likely yield a highly effective dose of Nitrates, adding a non-hormonal performance enhancement dimension to the product.
Coleus Forskohlii is generally standardized for the active component, Forskolin (sometimes spelled Forskohlin), which has implications for both weight-loss and increasing Testosterone. Forskohlin works by increasing Cyclic Adenosine Monophosphat (cAMP), a signaling molecule which, when elevated, can induce a wide variety of physiological changes including increased Tesetosterone, increased lean body mass, and decreased fat mass.
A 2005 study, published in “Obesity Research”, found that Forskohlin (25mg/day for 12 weeks) increased Testosterone (total test increased 16%, free test increased 3.4%) and favorably influenced body composition in obese men. Though the effects of Forskohlin on Testosterone levels in humans have not been studied extensively, Forskohlin is quite reliable at increasing cAMP, and cAMP is quite reliable at increasing Testosterone. So ultimately, Forskohlin possesses a sound mechanism by which it can positively influence Testosterone levels in humans.
THE BOTTOM LINE
Tropinol XP is one of the more distinguished, less generic Testosterone boosters we’ve reviewed, and iForce certainly makes use of some obscure ingredients. The inclusion of Forskohlin helps to guarantee atleast a slight/moderate increase in Testosterone, while Fadogia agrestis could potentially elevate Testosterone quite significantly. At about $1.4 per four capsules (daily recommendation), Tropinol XP is appropriately priced given the cost of most test-boosters and the potential for actually boosting Test. If your current DAA test-booster quite cutting it, Tropinol XP may be worth a shot (though it is still speculative).
- Yakubu, M. T., M. A. Akanji, and A. T. Oladiji. “Aphrodisiac potentials of the aqueous extract of Fadogia agrestis (Schweinf. Ex Hiern) stem in male albino rats.” Asian Journal of Andrology 7.4 (2005): 399-404.
- Syrov, V. N., and A. G. Kurmukov. “[Experimental study of the anabolic activity of 6-ketoderivatives of certain natural sapogenins].” Farmakologiia i toksikologiia 39.5 (1975): 631-635.
- Godard, Michael P., Brad A. Johnson, and Scott R. Richmond. “Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men.” Obesity Research 13.8 (2005): 1335-1343.
- Murphy, Margaret, et al. “Whole beetroot consumption acutely improves running performance.” Journal of the Academy of Nutrition and Dietetics 112.4 (2012): 548-552.
- Wylie, Lee J., et al. “Dietary nitrate supplementation improves team sport-specific intense intermittent exercise performance.” European journal of applied physiology 113.7 (2013): 1673-1684.
- Hoon, Matthew W., et al. “The effect of nitrate supplementation on exercise performance in healthy individuals: a systematic review and meta-analysis.”International Journal of Sport Nutrition & Exercise Metabolism 23.5 (2013).