Extreme Jitter Free Fat Burner is Top Secret Nutrition’s attempt at a stim-free weight-loss solution and, while we wouldn’t say they nailed it, the formula is relatively well-rounded.
WHITE KIDNEY BEAN:
White Kidney Bean is actually not a “fat burner” at all, but more of a calorie blocker. Both in vitro, and in vivo studies have demonstrated the ability of White Kidney Bean to block the absorption of carbohydrates, when consumed simultaneously, via inhibition of amylase (a digestive enzyme responsible for the absorption of starches). By reducing carbohydrate absorption, WKB may mimic the effects of a calorie restricted diet to some degree. While all studies have confirmed that there is some carb-blocking effect, the degree tends to vary and the total weight loss effect is likely influenced by many individual factors.
A 2004 study from “Alternative Medicine Review” found that Phase 2 (a patented White Kidney Bean extract) supplementation resulted in a trend towards weight-loss, but did not achieve statistical significance. A 2007 study, published in the “International Journal of Medical Sciences”, found that White Kidney Bean extract (445mg) was able to reduce bodyweight in slightly overweight human subjects.
So, while White Kidney Bean extract can certainly act as an effective carb-blocker, leading to a decrease in body weight over time, the degree of efficacy tends to vary so individual differences likely play a large role.
GREEN COFFEE EXTRACT:
Green Coffee Extract (GCE) conatins Chlorogenic Acid which is similar to White Kidney Bean in terms of mechanism of action (blocks carb absorption).
A 2007 study, published in the “Journal of International Medical Research”, found that 12 weeks of Green Coffee (450-500mg Clorogenic Acid) supplementation resulted in a reduction (6.9%) in glucose absorption in healthy volunteers. Researchers also noted average weight loss of 5.4 kg (almost 12 lbs) over the duration of the study in the group receiving the Green Coffee Extract. These findings conflict with an earlier 2006 study in which Green Coffee Extract (yielding 140mg Chlorogenic Acid) supplementation did not result in weight loss over the same 12 week period. The obvious difference between these two studies is that the dose of the first (positive) study was about 3 times the dose used in the second (negative) study. A 2012 study found that adults who consumed GCE (containing about 315mg Chlorogenic Acid) daily lost an average of 8kg with the average reduction in body fat being about 4%. Though GCE has shown mixed results in various studies, clear efficacy has been demonstrated at high enough doses (at least 300mg Chlorogenic Acid).
So, while Chlorogenic Acid can certainly be an effective weight-loss supplement, consuming a high enough dose is critical. Unfortunately, the exact dose of Green Coffee Extract present in the Extreme Jitter Free Fat Burner formula is unknown, let alone the Chlorogenic Acid content of the Green Coffee Extract. So, while its certainly possible that there is an effective dose, we can’t be certain.
Guarana is a plant native to the Amazon, the fruit of which contains Caffeine as well as related chemical compounds such as Theobromine and Theophylline (both cardiac stimulants with less of a mental effect). Although Guarana is touted as being a sort of “slow-release” form of caffeine, a study published in the “Journal of Pharmacy and Pharmacology” found there was no difference in the absorption rates of Caffeine from Guarana as opposed to Caffeine Anhydrous (synthetic) in rats. Human studies have yet to be confirmed, but given these preliminary findings, there is certainly no reason to believe Guarana would absorb any differently in humans.
The fat-burning capabilities of Guarana are mostly due to the Caffeine present, so in the context of Ab Igniter Black (or any fat-burner), we’d simply consider Guarana another source of Caffeine. Extreme Jitter Free Fat Burner contains 40mg of Caffeine from Guarana, which is a pretty low dose, even for those who don’t regularly consume Caffeine. At a dose this low, it is unlikely any of the side effects associated with higher Caffeine intake would be apparent (hence the name “Jitter Free”).
Raspberry Ketone (RK), a molecular constituent of Raspberries, has become a popular weight-loss additive in dietary supplements. However, the research regarding RK as a fat-burning ingredient is extremely limited and there is actually no direct evidence the ingredient is effective in oral, supplemental doses. In vitro studies using very high concentrations have shown positive results, but human studies are non-existent. The only human study that exists grouped RK in with several other popular weight loss ingredients so the effects cannot be attributed to Raspberry Ketone. Even in rat studies, RK fail to show any significant fat-burning effects. The overall consensus of the scientific community is that Raspberry Ketone is nothing more than industry hype.
Coleus Forskohlii is an Ayurvedic herb which has been studied (though not extensively) for its potential as a weight-loss agent/testosterone booster. The active component, Forskohlin, has been demonstrated to increase Cyclic Adenosine Monophosphate (cAMP), the result of which is an increase in the rate of fat-loss. A 2005 study, published in the “Journal of the International Society of Sports Nutrition”, found that 25mg Forskohlin twice a day for 12 weeks was able to prevent weight gain compared to the control group in overweight women. Another 2005 study, the subjects of which were overweight men, found that the same dose (25mg) was able to favorably influence body composition (i.e. less fat, more lean mass), which corresponded with an increase in testosterone over 12 weeks. A more recent 2011 study noted a roughly 2.5% decrease in BMI after 2 months of supplementation. Ultimately, Forskohlin may certainly result in weight-loss or at the very least, prevent weight gain. These effects may be more apparent in men, as an increase in cAMP also increases Testosterone, which inherently burns fat and increases lean muscle mass.
The exact dose of Forskohlin present in the Extreme Jitter Free Fat Burner formula is unknown, but given that ForsLean (patented form used in theformula), is generally about 95% Forskohlin, its certainly possible that it contains an effective 25mg dose.
THE BOTTOM LINE:
As far as non-stimulant based fat-burners go, Extreme Jitter Free is actually pretty effective. Aside from Raspberry Ketone, every ingredient in the formula has demonstrated some degree of efficacy with regards to weight-loss, and while we can’t be sure of the exact doses of any individual ingredient, based on the 1035mg proprietary blend, there are no immediate red flags with regards to dosing. For maximum benefits we’d recommend consuming 3 servings a day, and at a little under 50 cents per dose, this sort of dosing protocol wouldn’t be unreasonably expensive (compared to similar products). Overall, for those looking for a non-stimulant based weight-loss solution, Top Secret Nutrition’s Extreme Jitter Free Fat Burner may be worth a shot.
[expand title=”REFERENCES” tag=”h5″]
- Layer, P., G. L. Carlson, and E. P. DiMagno. “Partially purified white bean amylase inhibitor reduces starch digestion in vitro and inactivates intraduodenal amylase in humans.” Gastroenterology 88.6 (1985): 1895-902.
- Layer LAYER, PETER, et al. “Effect of a purified amylase inhibitor on carbohydrate tolerance in normal subjects and patients with diabetes mellitus.” Mayo Clinic Proceedings. Vol. 61. No. 6. Elsevier, 1986.
- Layer Udani, Jay, Mary Hardy, and Damian C. Madsen. “Blocking carbohydrate absorption and weight loss: a clinical trial using Phase 2™ brand proprietary fractionated white bean extract.” Alternative medicine review 9.1 (2004): 63-69.
- Layer Celleno, Leonardo, et al. “A dietary supplement containing standardized Phaseolus vulgaris extract influences body composition of overweight men and women.” International journal of medical sciences 4.1 (2007): 45.
- Layer Watanabe, Takuya, et al. “The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension.”Clinical and experimental hypertension 28.5 (2006): 439-449.
- Layer Thom, E. “The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people.” Journal of International Medical Research 35.6 (2007): 900-908.
- Layer Vinson, Joe A., Bryan R. Burnham, and Mysore V. Nagendran. “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects.”Diabetes, metabolic syndrome and obesity: targets and therapy 5 (2012): 21.
- Bempong, Daniel K., and Peter J. Houghton. “Dissolution and Absorption of Caffeine from Guarana.” Journal of Pharmacy and Pharmacology 44.9 (n.d.): 769-71.
- Layer Wang, Lili, Xianjun Meng, and Fengqing Zhang. “Raspberry ketone protects rats fed high-fat diets against nonalcoholic steatohepatitis.” Journal of medicinal food 15.5 (2012): 495-503.
- Layer Park, Kyoung Sik. “Raspberry ketone increases both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes.” Planta medica 76.15 (2010): 1654.
- Layer Morimoto, Chie, et al. “Anti-obese action of raspberry ketone.” Life sciences77.2 (2005): 194-204.
- Layer Henderson, Shonteh, et al. “Effects of coleus forskohlii supplementation on body composition and hematological profiles in mildly overweight women.” J Int Soc Sports Nutr 2.2 (2005): 54-62.
- Layer Godard, Michael P., Brad A. Johnson, and Scott R. Richmond. “Body composition and hormonal adaptations associated with forskolin consumption in overweight and obese men.” Obesity Research 13.8 (2005): 1335-1343.
- Layer Jagtap, Madhavi, H. M. Chandola, and B. Ravishankar. “Clinical efficacy of Coleus forskohlii (Willd.) Briq.(Makandi) in hypertension of geriatric population.”Ayu 32.1 (2011): 59.