Conquest HD is 1st Phorm’s three-ingredient test-booster which consists of D-Aspartic Acid, Agmatine, and Rosemary Leaf Extract…[Skip to the Bottom Line]
D-Aspartic Acid is one of the most popular test-boosting ingredients these days because, unlike many, it has been studied in humans and has actually been shown to boost Testosterone in healthy individuals, though this increase appears to be short-lived.
We discuss D-Aspartic Acid in-depth in this article, but thing to takeaway here is this: D-Aspartic Acid may boost Testosterone levels in the short-term but this won’t necessarily result in noticeable increases in lean muscle mass (because it doesn’t last long enough).
1st Phorm lists the amount of DAA in Conquest HD at 3120mg, a precise clinical dose.
Agmatine is common in pre-workout supplements these days as a pump-inducing ingredient, but there is also preliminary evidence which indicates it can induce the secretion of Luteinizing Hormone (LH), which can in turn trigger Testosterone production.
A 1995 study found that rats treated with Agmatine experienced increased LH secretion in a dose-dependent manner.
Since then, no human studies have been conducted so we don’t have much to go on here. 1st Phorm lists the amount of Agmatine in Conquest HD at 1000mg/serving, a pretty sizeable dose as far as most Agmatine-containing products go, but not necessarily effective for increasing increasing Test levels.
ROSEMARY LEAF EXTRACT:
Rosemary contains Ursolic Acid (1st Phorm does not disclose how much) which is often touted as an Aromatase inhibitor. Indeed, Ursolic Acid (not necessarily from Rosemary) has demonstrated aromatase inhibiting properties in vitro, but human studies are non-existent.
It seems unlikely that, at whatever dose is present in Conquest HD, that Rosemary would actually have a critical impact on Testosterone levels via Aromatase Inhibition.
THE BOTTOM LINE:
The Testosterone-boosting potential of Conquest HD is mostly dependent on D-Aspartic Acid and therefore may be short-lived and will not necessarily induce the sort of lean muscle mass gains that a longer-term increase in Testosterone levels would facilitate. Given that D-Aspartic Acid and Agmatine could be purchased separately for substantially less than the cost of Conquest HD, we have to recommend passing on this one.
[expand title=”REFERENCES” tag=”h5″]
- D’Aniello, Gemma, et al. “d-Aspartate, a key element for the improvement of sperm quality.” Advances in Sexual Medicine 2 (2012): 45.
- Topo, Enza, et al. “The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.” Reprod Biol Endocrinol 7.120 (2009): 6.
- Willoughby, Darryn S., and Brian Leutholtz. “d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men.” Nutrition Research 33.10 (2013): 803-810.
- D’Aniello, Autimo, Anna Di Cosmo, Carlo Di Cristo, Lucio Annunziato, Leonard Petrucelli, and George Fisher. “Involvement of D-Aspartic Acid in the Synthesis of Testosterone in Rat Testes.” Life Sciences 59.2 (1996): 97-104.
- Kalra, Satya P., et al. “Agmatine, a novel hypothalamic amine, stimulates pituitary luteinizing hormone release in vivo and hypothalamic luteinizing hormone-releasing hormone release in vitro.” Neuroscience letters 194.3 (1995): 165-168.
- Shin, In-Sik, et al. “Ursolic acid reduces prostate size and dihydrotestosterone level in a rat model of benign prostatic hyperplasia.” Food and Chemical Toxicology 50.3 (2012): 884-888.
- Gansser, Dietmar, and Gerhard Spiteller. “Aromatase inhibitors from Urtica dioica roots.” Planta medica 61.2 (1995): 138-140.
- Gnoatto, Simone CB, et al. “Evaluation of ursolic acid isolated from Ilex paraguariensis and derivatives on aromatase inhibition.” European journal of medicinal chemistry 43.9 (2008): 1865-1877.