Thermogenic Shred is a weight-loss supplement by Iovate relased under the Six Star Pro Nutrition brand. It contains several ingredients which can be found in many other fat-burners so we wouldn’t consider it particularly revolutionary in any sense…FIND IT HERE
Caffeine is a well-established ergogenic aid, oral consumption of which triggers the release of Catcholamines (Noradrenaline, Dopamine, Adrenaline, etc.), generally inducing a state of increased alertness, focus, and perceived energy.
Additionally, Caffeine can enhance calcium-ion release in muscle tissue, which directly increases muscle contraction force. Rather than discuss dozens of studies, we’ll leave it at this: Caffeine is an extremely effective ergogenic aid, though tolerance build-up is certainly an issue to keep in mind.
Like several other recently released Iovate (Six Star Pro Nutrition, MuscleTech, Hydroxycut, Xenadrine) products, Thermogenic Shred contains 270mg of Caffeine per serving, not what most would consider a “low” dose but not necessarily over the top either.
Green Coffee Extract
Green Coffee Extract contains Chlorogenic Acid which has been shown to block carbohydrate absorption in humans, thus mimicking the effects of a reduced carb-diet. We discuss Green Coffee Extract in depth in this article, but most likely users would need to consume at least 2 servings of Thermogenic Shred to benefit from Green Coffee Extract.
With the overwhelming amount of evidence indicating that Theanine enhances the positive effects of Caffeine AND reduces the negative effects, it amazes us that more brands don’t use it. Theanine and Caffeine is one of the few combinations that can actually be considered synergistic, rather than merely additive.
Theanine is effective in doses of 50-200mg and the synergistic benefits depend on how much Caffeine is being consumed with it. Thermogenic Shred contains 100mg of Theanine per serving, a helpful addition to a formula that contains multiple stimulants.
Cocoa Extract is generally standardized for Theobromine, a chemical relative of Caffeine but that remains seriously under-researched with regards to weight-loss potential. Preliminary studies indicate that Theobromine is a cardiac stimulant, but it does not appear to have psychoactive effects like Caffeine (i.e. energy).
Yohimbine acts as an alpha(2) receptor antagonist, meaning it inhibits the receptor responsible for blocking lipolysis (breakdown of fat). By blocking the action of this receptor Yohimbine allows for more lipolysis than would otherwise be possible from exercise.
We discuss the fat-burning implications of Yohimbine further in this article, but it can be very effective, assuming the right dose. That said, Since Six Star only lists the total amount of Yohimbe, not Yohimbine, present in Thermogenic Shred, we can’t be sure of the dose.
Grains of Paradise
Grains of Paradise has been to shown to increase metabolic rate in response to a physiological stressor (in this case cold exposure) via activation of Brown Adipose Tissue. It’s potential for weight-loss is discussed in this article.
Six Star lists the total amount of Grains of Paradise extract in Thermogenic Shred at 20mg per serving.
Though commonly standardized for Capsaicin content alone, Cayenne also contains other compounds, collectively referred to as Capsaicinoids, which include Dihydrocapsaicin and Nordihydrocapsaicin.
A 2007 study noted an increase in fat oxidation (relative to placebo) during low intensity exercise in healthy adult males who consumed 150mg of capsaicin one hour before exercise.
Elsewhere, different Capsinoids (possibly also found in Cayenne), have been shown to exert similar effects. While Cayenne Pepper is not likely to induce drastic weight-loss by itself, it does certainly help to round out the thermogenic component of Thermogenic Shred.
The Bottom Line
Thermogenic Shred contains several known weight-loss ingredients as well as some that we’d still consider a little speculative. Most of the ingredients are dosed effectively and, at two servings daily, Thermogenic Shred may induce some weight-loss when combined with exercise. We wouldn’t say it’s a game changing formula but, overall, it’s not a bad option if the price is right.
Still not sure which fat-burner is right for you? Check out our Top 10 Fat-Burners List!
- Watanabe, Takuya, et al. “The blood pressure-lowering effect and safety of chlorogenic acid from green coffee bean extract in essential hypertension.”Clinical and experimental hypertension 28.5 (2006): 439-449.
- Vinson, Joe A., Bryan R. Burnham, and Mysore V. Nagendran. “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects.”Diabetes, metabolic syndrome and obesity: targets and therapy 5 (2012): 21.
- Graham, T. E., and L. L. Spriet. “Metabolic, catecholamine, and exercise performance responses to various doses of caffeine.” Journal of Applied Physiology 78.3 (1995): 867-874
- Graham, Terry E. “Caffeine and exercise.” Sports medicine 31.11 (2001): 785-807.
- Ebashi, S., and Mi Endo. “Calcium and muscle contraction.” Progress in biophysics and molecular biology 18 (1968): 123-183
- Poisner, Alan M. “Caffeine–Induced Catecholamine Secretion: Similarity to Caffeine–Induced Muscle Contraction.” Experimental Biology and Medicine142.1 (1973): 103-10
- Kaats, Gilbert R., et al. “A 60day double-blind, placebo-controlled safety study involving< i> Citrus aurantium(bitter orange) extract.” Food and Chemical Toxicology 55 (2013): 358-362.
- Ostojic, Sergej M. “Yohimbine: the effects on body composition and exercise performance in soccer players.” Research in Sports Medicine 14.4 (2006): 289-299.
- Graham, Terry E., Danielle S. Battram, Flemming Dela, Ahmed El-Sohemy, and Farah S.L. Thong. “Does Caffeine Alter Muscle Carbohydrate and Fat Metabolism during Exercise?” Applied Physiology, Nutrition, and Metabolism 33.6 (2008): 1311-31
- Thom, E. “The effect of chlorogenic acid enriched coffee on glucose absorption in healthy volunteers and its effect on body mass when used long-term in overweight and obese people.” Journal of International Medical Research 35.6 (2007): 900-908.
- Haskell, Crystal F., et al. “The effects of L-theanine, caffeine and their combination on cognition and mood.” Biological psychology 77.2 (2008): 113-122.
- Owen, Gail N., et al. “The combined effects of L-theanine and caffeine on cognitive performance and mood.” Nutritional neuroscience 11.4 (2008): 193-19
- Einöther, Suzanne JL, et al. “L-theanine and caffeine improve task switching but not intersensory attention or subjective alertness.” Appetite 54.2 (2010): 406-409.
- Giesbrecht, Timo, et al. “The combination of L-theanine and caffeine improves cognitive performance and increases subjective alertness.” Nutritional neuroscience 13.6 (2010): 283-290.
- Nedergaard, Jan, Tore Bengtsson, and Barbara Cannon. “Unexpected evidence for active brown adipose tissue in adult humans.” American Journal of Physiology-Endocrinology and Metabolism 293.2 (2007): E444-E452.
- Cannon, Barbara, and J. A. N. Nedergaard. “Brown adipose tissue: function and physiological significance.” Physiological reviews 84.1 (2004): 277-359.
- Capsaicin Ingestion during Aerobic Exercise in Healthy Men.” Journal of Nutritional Science and Vitaminology 53.2 (2007): 124-32
- Ohnuki, Koichiro, et al. “Administration of capsiate, a non-pungent capsaicin analog, promotes energy metabolism and suppresses body fat accumulation in mice.” Bioscience, biotechnology, and biochemistry 65.12 (2001): 2735.
- WATANABE, TATSUO, et al. “Adrenal sympathetic efferent nerve and catechol secretion excitation caused by capsaicin in rats.” (1988).
- Sugita, Jun, et al. “Grains of paradise (Aframomum melegueta) extract activates brown adipose tissue and increases whole-body energy expenditure in men.”British Journal of Nutrition 110.04 (2013): 733-738.