Purus Labs Creagyn Review

Creagyn is the second unflavored pre-workout augmentor to be released by Purus Labs, the first being Noxygen. It contains just two active ingredients: HydroMax Glycerol and MagnaPower Creatine Magnesium Chelate…

Purus Labs Creagyn



As mentioned in the Taurine section, Glycerol is osmolytic, meaning it draws water into the cell. It is by this mechanism that Glycerol can preserve hydration status in the cell which explains why it has also been shown to enhance performance during extended exercise where dehydration would be a contributing factor.

So, as a performance enhancer, Glycerol may only induce noticeable enhancements during extended exercise (2 hours or more usually). As a pump-agent, Glycerol can be quite effective and the 1.5g dose of HydroMax present in Creagyn definitely has what it takes to induce a noticeable pump.

Creatine Magnesium Chelate

Creatine Magnesium Chelate is Creatine bonded to Magnesium, and was originally invented because of Magnesium’s crucial role in Creatine metabolism.

A 2004 study, published in “The Journal of Strength & Conditioning Research”, found that 2.5g ofCreatine Magnesium Chelate was equivalent to the same dose of Creatine Monohydrate with regards to increasing 1 rep max in trained men.

Although Creatine Magnesium Chelate appears no more effective than Monohydrate in terms of physical performance enhancement, a 2003 study published in “Metabolism” did note that Creatine Magnesium Chelate may result in less water retention. However, this has only been noted at low doses. Over the course of a Creatine cycle, when total muscle Creatine saturation occurs, the difference would likely become less apparent.

Creagyn contains 1g of MagnaPower per serving, not exactly what we like to see but potentially enough to augment any other Creatine-containing pre-workout supplement.

The Bottom Line

Creagyn may provide some pretty good pumps during workouts, but would need to be combined with an outside source of Creatine in order to yield an effective dose.

  1. Magal, M. E. I. R., et al. “Comparison of glycerol and water hydration regimens on tennis-related performance.” Medicine and science in sports and exercise35.1 (2003): 150-156.
  2. Wingo, Jonathan E., et al. “Influence of a pre-exercise glycerol hydration beverage on performance and physiologic function during mountain-bike races in the heat.” Journal of athletic training 39.2 (2004): 169.
  3. Hitchins, S., et al. “Glycerol hyperhydration improves cycle time trial performance in hot humid conditions.” European journal of applied physiology and occupational physiology 80.5 (1999): 494-50
  4. Brilla, L. R., et al. “Magnesium-creatine supplementation effects on body water.” Metabolism 52.9 (2003): 1136-1140

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