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Molecular Nutrition X-Factor Review

X-Factor is a muscle-builder by Molecular Nutrition which features Arachidonic Acid as it’s primary active ingredient…

Molecular Nutrition X-Factor

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ARCHIDONIC ACID

In a 2007 study published in the “Journal of the International Society of Sports Nutrition”, subjects received either 1g of Arachidonic Acid or a placebo each day for 50 days.  The group taking Arachidonic Acid experienced increases in peak power and average power, as assessed by a Wingate test.

A recent (2014) study conducted at the University of Tampa found that 1.5g of Arachidonic Acid daily for 8 weeks was able to increase strength, power, and lean body mass compared to the placebo group.

MECHANISM OF ACTION

Arachidonic Acid is used to produce the signaling molecules (eicosanoids), PGF(2α) and PGE2 which stimulate muscle protein synthesis when prompted by a physical stressor such as the stretching of muscle.

Blood levels of Arachidonic Acid tend to decrease substantially as a result of exercise, limiting the amount of muscle protein synthesis that can occur.  Supplementation is able to prevent this decrease from occurring.

THE BOTTOM LINE

Arachidonic Acid has some pretty clear implications as an ergogenic aid and should be considered by anyone looking to increase strength and/or muscle mass to a moderately noticeable degree.  When it comes to selecting the best source of Arachidonic Acid, X-Factor is as good as it gets since it is standardized to 40% Arachidonic Acid by weight.

REFERENCES
  1. Roberts, Michael D., et al. “Effects of arachidonic acid supplementation on training adaptations in resistance-trained males.” Journal of the International Society of Sports Nutrition 4.1 (2007): 1-13.
  2. Giordano, Rose M., et al. “Effects of dynamic exercise on plasma arachidonic acid epoxides and diols in human volunteers.” International Journal of Sport Nutrition andExercise Metabolism 21.6 (2011): 471.
  3. Markworth, James F., and David Cameron-Smith. “Arachidonic acid supplementation enhances in vitro skeletal muscle cell growth via a COX-2-dependent pathway.” American Journal of Physiology-Cell Physiology 304.1 (2013): C56-C67.
  4. Effects of Arachadonic Acid on Skeletal Muscle Mass, Strength, and Power. NSCA 2014 National Conference. July 9-12, 2014.

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