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Lecheek Nutrition AMPilean Pink Review

AMPilean Pink

AMPilean Pink is Lecheek Nutrition’s fat-burning/weight-loss formula which is aimed particularly at women…

 

AMPilean Pink is Lecheek Nutrition’s fat-burning/weight-loss formula which is aimed particularly at women…

[SKIP TO THE BOTTOM LINE]

DICAFFEINE MALATE:

Dicaffeine Malate is simply a combination of Caffeine and Malic Acid which is alleged to have longer-lasting effects and a smoother overall transition (no crash).  To be fair, these claims have not been substantiated at this time, but, at the very least, Dicaffeine Malate serves as another source of Caffeine.

So, in the context of AMPilean Pink, Caffeine serves as a way to “kick-start” the fat-burning process and may further amplify (or be amplified by) the effects of Octopamine.

DANDELION (TARAXACUM OFFICINALE):

Taraxacum  Officinale, also known as Dandelion, has a long history of use in alternative medicine as a diuretic. A 1993 study published in “Pharmaceutical Biology” pointed to the high potassium content as a possible reason for the diuretic of effect, though various compounds have been isolated and alleged to contribute to this effect.

A 2009 study, published in “The Journal of Alternative and Complementary Medicine” found thatsupplementation with Dandelion Extract caused more frequent urination in subjects, but a specific mechanism of action was not identified.

So, in the context of AMPilean Pink, Dandelion may help to keep off some water weight but since it does not attack fat directly we wouldn’t consider it a particularly useful ingredient.

OCTOPAMINE HCL:

Octopamine is a metabolite of Synephrine that is alleged to have similar fat-burner capabilities. In vitro, Octopamine has demonstrated a distinct affinity for beta-3 receptors, as opposed to the other two types.

Unfortunately, since beta-3 receptors mediate fat-loss in human white adipose tissue to a lesser degree than the other beta-receptors, Octopamine may be less potent than Synephrine in a practical setting.

GREEN COFFEE EXTRACT:

Green Coffee Extract contains Chlorogenic Acid which has been shown to block carbohydrate absorption in humans, thus mimicking the effects of a reduced carb-diet. We discuss Green Coffee Extract in depth in this article, but it seems fairly apparent that the dose present in AMPilean Pink is less than what could be considered a “clinical dose”.

GARCINIA CAMBOGIA EXTRACT (HYDROXYCITRIC ACID):

The primary bioactive in Garcinia Cambogia is Hydroxycitric Acid (HCA), which is alleged to reduce body weight via inhibition of ATP Citrate Lysase, an enzyme required for the synthesis of fatty acids from carbohydrates (de novo lipogenisis).

In theory, blocking this enzyme would essentially stop excess carbohydrates from being stored as fat. Unfortunately, while inhibition of ATP Citrate Lysase has resulted in weight-loss in rodents, the implications for humans are less promising, because de novo lipogenesis occurs less in humans than rodents.

We discuss Garcinia Cambogia in depth in this article, but the bottom line is that it isn’t particularly effective in humans, nor is the dose found in AMPilean Pink particularly high.

BIOPERINE:

Piper nigrum, also known as Black Pepper, contains Piperine. Several studies have found that black pepper extract, when combined with other supplements, has increased the absorption of those supplements (as measured by plasma levels).

Piperine’s ability to increase absorption of other compounds is due to the inhibition of certain enzymes which breakdown most compounds, as well as the slowing of intestinal transit (increasing the amount of time these compounds are exposed to the possibility of uptake).

In the context of AMPilean Pink, BioPerine is simply an absorption enhancer, though to what degree it enhances absorption, we don’t know.

THE BOTTOM LINE:

AMPilean Pink isn’t a particularly impressive formula and appears to be more of an attempt to capitalize off of the rising popularity of “for her” supplements, rather than something that is inherently more useful for women.  The fat-burning potential is pretty limited with this one.

REFERENCES
  1. Graham, T. E., and L. L. Spriet. “Metabolic, catecholamine, and exercise performance responses to various doses of caffeine.” Journal of Applied Physiology 78.3 (1995): 867-874
  2. Graham, Terry E. “Caffeine and exercise.” Sports medicine 31.11 (2001): 785-807.
  3. Ebashi, S., and Mi Endo. “Calcium and muscle contraction.” Progress in biophysics and molecular biology 18 (1968): 123-183
  4. Poisner, Alan M. “Caffeine–Induced Catecholamine Secretion: Similarity to Caffeine–Induced Muscle Contraction.” Experimental Biology and Medicine142.1 (1973): 103-10
  5. Râcz–Kotilla, Elisabeth, G. Racz, and Ana Solomon. “The action of Taraxacum officinale extracts on the body weight and diuresis of laboratory animals.”Planta medica 26.07 (1974): 212-217.
  6. Clare, Bevin A., Richard S. Conroy, and Kevin Spelman. “The diuretic effect in human subjects of an extract of Taraxacum officinale folium over a single day.”The Journal of Alternative and Complementary Medicine 15.8 (2009): 929-934.
  7. Hook, I., A. McGee, and M. Henman. “Evaluation of dandelion for diuretic activity and variation in potassium content.” Pharmaceutical biology 31.1 (1993): 29-34.
  8. Heymsfield, Steven B., et al. “Garcinia cambogia (hydroxycitric acid) as a potential antiobesity agent: a randomized controlled trial.” Jama 280.18 (1998): 1596-1600.
  9. Kim, Ji-Eun, et al. “Does Glycine max leaves or Garcinia Cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial.” Nutrition journal 10.1 (2011): 94.

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