If you’ve been involved or at least familiar with the supplement industry for a decade or so, you’ve probably heard all about Ephedrine.
This extremely controversial stimulant became one of the most popular, widely used fat-burning supplements of all time. That is, before it was banned.
But we’ll get into all those specifics later on, but first let’s talk about what your going to get out of this article.
By the end, you’ll know:
- What Ephedrine is
- How It Works
- What Kind Of Results You Can Expect
- The Potential Risks And Side Effects
- (Legal) Alternatives That Work Well
Pretty much everything you could possibly want to know about the most controversial (and popular) weight-loss supplements of all time.
It’s about time someone actually looked at both sides. Most of what you’ll read on the internet is either pro or anti-Ephedrine.
I’m just laying out the facts. My only goal is to help you make an informed decision, rather than experiment with a compound you know nothing about.
If we all took the time to learn a thing or to before ingesting this or that supplement, fewer hospitalizations and deaths would happen and the FDA wouldn’t be banning things left and right.
But I digress…
Back to the topic at hand.
What Is Ephedrine?
Ephedrine content has been analyzed in various species of Ephedra plants, including (but not limited to):
- Ephedra monosperma
- Ephedra fragilis
- Ephedra foeminea
- Ephedra alata
- Ephedra sinica
But so far, sizeable levels of Ephedrine have only been found in Ephedra sinica. That made this particular species of Ephedra the most commonly used in supplements prior to the ban.
Ephedrine is a fairly potent stimulant which can directly increase your metabolic rate (amount of calories you burn at rest) and can potentially enhance physical performance as well.
Thus, it’s one of the most sought after weight-loss drugs out there, but also one of the most controversial
Unfortunately (if you want to use it to lose fat), Ephedrine was banned by the FDA in 2004, allegedly over concerns that it may pose long-term health risks.
Not to mention, Ephedrine can be used to make Methamphetamine (another reason the government doesn’t like it much).
Although Ephedrine is banned for use in dietary supplements in the US, it remains extremely popular as a fat-loss agent.
There are some legal supplement alternatives, but nothing that works quite as well as Ephedrine.
How Does Ephedrine Work?
That means it directly stimulates Lipolysis, or fat-breakdown.
Lipolysis is the first step in getting rid of fat. By breaking down fat and releasing fatty acids into the blood stream, the body is more likely to use fat as an energy source (burning it).
To put it simply, your body has two types of receptors that regulate Lipolysis:
- Beta-receptors – Trigger Lipolysis
- Alpha-receptors – Stop Lipolysis
By directly binding to and activating beta-receptors (especially beta-2-receptors), Ephedrine increases the amount of calories you burn at rest (resting metabolic rate), most of which is fat.
All those extra calories must add up!
Or do they?
Let’s dig deeper…
Why Do People Use Ephedrine? What Are The Benefits?
The primary objective for most people who use Ephedrine is fat-loss.
As a stimulant, Ephedrine can potentially increase perceived energy levels, lift your mood, keep you awake, and suppress your appetite.
But the same can be said for many stimulants.
Ephedrine shines because, as a beta-receptor agonist, it’s inherently capable of increasing the amount of fat you burn, not to mention the appetite suppression and increased energy.
Now, the obvious question is:
How much fat-loss are we talking?
Alone, Ephedrine is capable of increasing your metabolic rate by 5-10%, all else equal.
You’ll lose maybe 2 pounds a month.
Combined with Caffeine, however, it’s more like 4 or 5 lbs per month. Now that’s actually pretty significant, especially if we’re talking mostly fat.
How is this possible, you ask?
Caffeine triggers the release of Catecholamines–a group of fat-burning chemicals which includes Dopamine and Noradrenaline–which have inherent fat-burning properties of their own.
Combined with ea beta-receptor agonist, Caffeine is the trigger that sets the fat-loss cycle in motion.
That’s why this particular combination has been studied so much…
Caffeine + beta-receptor agonist = more fat-loss than beta-receptor agonist alone.
Caffeine is also a known exercise performance enhancer on its own.
So naturally, most people combined the two in the first place. I mean, why lose 2 pounds of fat per month if you could lose 5 pounds a month, right?
Well, we’ll be sure to talk about the added risk that this poses a little later on, but first let’s talk about something nobody seems to know anything about…
What’s The Clinically Effective Dosage For Ephedrine?
Studies regarding pertaining to fat-loss tend to dose Ephedrine in 20mg or 25mg increments. Some studies use doses as low as 20 or 25mg.
So, dosing is pretty much all over the board with Ephedrine. Perhaps that’s why there’s been deaths linked to intoxication and why the FDA felt the need to ban it.
Perhaps if we could identify an effective, but safe dose, rather than jumping from 20mg/day to 200mg/day and ODing, some studies could investigate a few doses in the middle of that rather broad range.
After all, there’s a lot of different dosing options between 20mg and 150-200mg. Who thought it was a good idea to go that high?
I personally have never used Ephedrine, so I can’t offer any sort of anecdotal advise on this one.
What I will say though is that it is always better to start with a low dose of any stimulant, see what it does, then consider bumping it up if you think you need to.
I would definitely not recommend starting at the higher end of the clinical range, even if it’s been shown to be safe. You don’t want to find out the hard way that you have a low Ephedrine tolerance.
What Are The Potential Side Effects Of Ephedrine?
Like most drugs that work, Ephedrine has a fair amount of potential side effects that come with it. The minor side effects include:
- Rapid Heart Beat
The more serious side effects, you ask?
- Heart Attack
Of course, the more Ephedrine you take, the more likely it is that you’ll experience side effects. The same goes for any stimulant.
That’s yet another reason why it’s good to start with a low dose!
So yeah, Ephedrine is a serious stimulant. It definitely works, but like any good drug, bad things happen sometimes if you take too much.
Is Ephedrine Legal?
Like I said earlier, Ephedrine was banned for use in dietary supplements in 2004 by the FDA. It would be illegal to sell it as a dietary supplement or as an ingredient in a dietary supplement.
It is legal for pharmaceutical companies to use in cold medications, but due to the meth epidemic, alternative routes are being explored.
In 2005, the Bush administration passed the Combat Of Methamphetamine Epidemic Act which placed a ton of restrictions and regulations on the sale of Ephedrine.
Needless to say, that’s kind of what made the supplement industry back off.
On the next stimulant!
That ended up being DMAA, which is still either in the process of being banned or unbanned…
Not really sure what’s going on with that.
The point is that while it’s not illegal to possess or use Ephedrine, it’s difficult to get it reliably. You have to order it off shady research chemical websites or international online pharmacies.
You’re not going to find it on Amazon, that’s for sure.
Legal Ephedrine Alternatives (Supplements)
As with most drugs, there are legal supplements that serve as alternatives. Needless to say, no supplement is going to be as effective as it’s pharmaceutical counterpart, but they also tend to come with less risk.
So, if you’re someone who cares about you’re health (hopefully you are), you should consider going with a less risky, still moderately effective alternative.
You can easily construct a fat-burning powerhouse by combining a few simple supplements.
Synephrine is considered by many to be the next best thing to Ephedrine. In many ways, it is.
Like Ephedrine, Synephrine is a beta-receptor agonist which has been shown to increase metabolic rate…
Just not as much as Ephedrine.
There’s no doubt that Synephrine is less effective than Ephedrine, but it also has a stronger safety profile. No deaths have been attributed directly to Synephrine.
In fact, it’s pretty mild in terms of the stimulant effects.
Like Synephrine, Higenamine is a beta-receptor agonist, but the stimulant properties are more noticeable.
For this reason, it serves as a key ingredient in many high-stim pre-workout supplements. On it’s own, the stimulant properties are definitely noticeable, especially once you start to work out.
They may be further enhanced though by combining Higenamine and Rauwolscine. You could combine Higenamine with Synephrine as well, but they basically do the same thing so that may just be over-kill.
Caffeine forms the basis for pretty much any effective fat-burning supplement. There are some exception, like Legion’s Phoenix which is still effective without Caffeine.
But even that supplement is designed to be stacked with Caffeine from an alternate source.
The truth is, Caffeine is pretty useful for burning fat, especially if you haven’t developed a tolerance yet.
It triggers the release of Catecholamines, a group of fat-burning hormones which are also responsible for the feelings of mental altertness and mood enhancement that first-time Caffeine use is known to induce.
In fact, many of the studies on Ephedrine were in combination with Caffeine, and it’s quite clear that Caffeine + Ephedrine burns considerably more fat than Ephedrine alone.
So if you’re trying to construct the ideal fat-burner from individual ingredients, Caffeine deserves a place.
Depending on your tolerance, doses of 100-400mg/day are okay. Just test out a lower dose first if you’re new to Caffeine.
My Personal Opinion On Ephedrine As A Fat-Loss Solution
Like I said, I’ve never used Ephedrine, the reason being that it just doesn’t seem worth it to me. Sure, Ephedrine can help you lose a few pounds a month (maybe even 5 lbs or so if combined with Caffeine), but so can making simple adjustments to your:
It’s always best to start with the basics before considering any kind of drug. It may be faster, but make no mistake:
There are risks and potential side effects.
You’ve been warned!
The Bottom Line On Ephedrine
Ephedrine is far from the magical weight-loss supplement/drug that it’s often made out to be. In fact, Clenbuterol is probably stronger and carries similar risks.
The combination of Caffeine and Ephedrine, however, is definitely one of the most powerful fat-burning duos there is.
Just be careful with dosing. People keep over-doing it instead of being smart about it and working their way up. That’s why all the good stuff gets banned guys.
Have Anything To Add About Ephedrine? Personal Experiences You Wouldn’t Mind Sharing? Comment Below…