Anabolic Freak consists of a relatively concise blend of ingredients aimed at boosting Testosterone and “promoting healthy Estrogen levels”…[Skip to the Bottom Line]
D-ASPARTIC ACID (DAA):
D-Aspartic Acid is an amino acid that acts as a precursor to N-Methyl-D-aspartic acid (NMDA), which takes on a similar role to the excitatory neurotransmitter glutamic acid. In rats, D-Aspartic acid supplementation was found to increase testosterone significantly. For this reason, it has become a popular additive in workout supplements. Out of the three human studies done specifically to test the effect of D-Aspartic Acid on testosterone, two have shown a significant increase in testosterone levels.
One study, the subjects of which were infertile men (low testosterone) showed a significant increase in tesosterone after 90 days of supplementation. Another study, this time on men with normal test levels, found a significant increase in testosterone after just 12 days.
However, a 2013 study found that athletes who supplemented with D-Aspartic Acid for 28 days showed no difference in testosterone levels. It is possible that D-Aspartic Acid did not increase testosterone in athletes because their testosterone levels were already maximized.
Ultimately, D-Aspartic Acid appears effective for increasing testosterone in individuals with low testosterone levels, and may be effective in the short term for individuals with normal testosterone levels as well.
HONG JING TIAN (RHODIOLA ROSEA):
Rhodiola Rosea has a long history of use as an adaptogen. An adaptogen is a plant (or extract) that decreases the body’s sensitivity to stress. The herb has been shown to increase endurance and thus exercise performance. Preliminary studies in animals have shown that Rhodiola Rosea produces anabolic effects similar to low dose testosterone treatment. One human trial, to determine a possible role in erectile dysfunction, found that subjects who consumed 150-200mg Rhodiola Rosea daily for three months experienced heightened sexual function. Whether this was a direct result of increased testosterone is unknown, but given the preliminary support from the animal studies, it is certainly a possibility.
Resveratrol is a compound found in Red Wine which has gained a lot of traction in the supplement industry primarily because of claims that it can increase lifespan. Needless to say, it would be difficult to substantiate these claims in humans (the studies would be very long), so for now we don’t buy it. In the context of the Test Freak formula, Resveratrol is alleged to serve a different purpose. PharmaFreak claims that Resveratrol “Supports Testosterone-To-Estrogen Conversion Control”. In a 2006 in vitro study found that Resveratrol effectively reduced the conversion of Testosterone to Estrogen in breast cancer cells. However, no human studies have been conducted to replicate these findings so at this time there is simply not enough to evidence to conclude Resveratrol is an effective aromatase inhibitor.
THE BOTTOM LINE:
The only ingredien in Anaolic Freak that has the potential to raise testosterone is D-Aspartic Acid, which may cause a short-lived (a few weeks) rise testosterone levels. Whether this temporary rise results in any meaningful increase in strength or lean muscle mass remains to be determined. However, Anabolic Freak contains roughly half the dose of D-Aspartic Acid required to produce this effect (according to the studies), so two servings would likely have to be consumed. At about $1.15 per serving, taking two servings at a time may be costly to some.
- Wang, Yun, et al. “The red wine polyphenol resveratrol displays bilevel inhibition on aromatase in breast cancer cells.” Toxicological Sciences 92.1 (2006): 71-77.
- D’Aniello, Autimo, et al. “Involvement of D-aspartic acid in the synthesis of testosterone in rat testes.” Life sciences 59.2 (1996): 97-104.
- Topo, Enza, et al. “The role and molecular mechanism of D-aspartic acid in the release and synthesis of LH and testosterone in humans and rats.” Reprod Biol Endocrinol 7 (2009): 120.
- Willoughby, Darryn S., and Brian Leutholtz. “d-Aspartic acid supplementation combined with 28 days of heavy resistance training has no effect on body composition, muscle strength, and serum hormones associated with the hypothalamo-pituitary-gonadal axis in resistance-trained men.” Nutrition Research 33.10 (2013): 803-810.
- Eagon, Patricia K., et al. “Evaluation of the medicinal botanical Rhodiola rosea for estrogenicity.” Proceedings of the American Association for Cancer Research 2004.1 (2004): 663.
- Khanum, Farhath, Amarinder Singh Bawa, and Brahm Singh. “Rhodiola rosea: a versatile adaptogen.” Comprehensive reviews in food science and food safety 4.3 (2005): 55-62.