Super Cissus is USP Labs’ one ingredient supplement containing only Cissus Quadrangularis. Preliminary evidence indicates that Cissus may quite effective as a joint-support/joint-repair supplement…[Skip to the Bottom Line]
Cissus Quadrangularis is a plant found in Africa and parts of Asia. It has a long history of use by the inhabitants in the areas it is indigenous to, but has recently made its way into fitness supplements. It is alleged to have anti-inflammatory, analgesic (pain relief), and antioxidant properties. Of particular interest is Cissus Quadrangularis’s effects on bone health.
A 2003 study in the Journal of Ethnopharmacology found that the extract possessed “a definite antiosteoporotic effect” in rats. For anyone who suffers from a bone debilitating disease such as osteoporosis, this is good news, but Cissus has implications for athletes as well. While it has proven effective in decreasing recovery time from bone injury, it does so by influencing early regeneration of connective tissue, meaning it may be beneficial for joints as well.
While more studies are needed to directly study the effects of Cissus supplementation on connective tissue, these findings certainly imply benefits for bodybuilders and athletes whose joints are constantly under stress. One human study found that subjects with exercise related injuries who recieved 3200mg of Cissus Quadrangularis extract over an 8 week period reported a decrease in joint pain. However, given that the nature of the results was somewhat subjective, further study is needed to determine a more objective mechanism of action.
THE BOTTOM LINE:
More human studies may very well reveal a mechanism of action by which Cissus Quadrangularis benefits joint and bone health, thereby making it an effective recovery supplement for athletes and bodybuilders as well as those suffering from such conditions as osteoporosis. USP’s Super Cissus is priced at about 42 cents per 1600mg dose, which is about average as far as Cissus supplements go.
- Chidambara Murthy, K. N., et al. “Antioxidant and antimicrobial activity of Cissus quadrangularis L.” Journal of medicinal food 6.2 (2003): 99-105.
- Shirwaikar, Annie, Saleemulla Khan, and S. Malini. “Antiosteoporotic effect of ethanol extract of< i> Cissus quadrangularis Linn. on ovariectomized rat.”Journal of ethnopharmacology 89.2 (2003): 245-250.
- Bloomer, R. J., et al. “Cissus quadrangularis reduces joint pain in exercise-trained men: A pilot study.” The Physician and sportsmedicine 41.3 (2013): 29-35.