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Shred Her Review

Shred Her

Shred Her is NLA’s fat-burner released under the NLA For Her brand. Like most “for her” supplements, there is nothing about the formula that makes it inherently geared toward women…

 

Shred Her is NLA’s fat-burner released under the NLA For Her brand. Like most “for her” supplements, there is nothing about the formula that makes it inherently geared toward women…[Skip to the Bottom Line]

Green Tea Extract

Multiple studies have confirmed Green Tea Extract appears to be able to induce fat-loss. Although this effect was originally thought to be related to caffeine content, more recent research has pointed to a green tea catechin known as Epigallocatechin gallate as the compound primarily responsible for these effects.

Epigallocatechin gallate (EGCG) is an antioxidant found in green tea, and is a member of the group of antioxidants known as catechins. In addition to these antioxidant properties, EGCG has demonstrated the ability to induce fat –loss when combined with caffeine, more than just caffeine alone. EGCG works synergistically with caffeine with regards to its effect on noradrenaline.

Caffeine boosts noradrenaline while EGCG inhibits catechol-o-methyl transferase (COMT), the enzyme responsible for the degredation of noradrenaline. So, caffeine increases noradrenaline, while EGCG prevents it’s degradation. When combined, the effect is increased levels of noradrenaline which triggers lipolysis (fat burning).

Taurine

Considered a beta-amino acid, Taurine plays a variety of roles in the body. It is most concentrated in the brain and liver, but is found in some amount virtually everywhere in the body. However, aside from it’s amino acid-like functions, Taurine also functions as a relatively potent antioxidant.

In a 2011 study, Taurine supplementation was shown to significantly decrease oxidative stress in skeletal muscle following exercise. Prior to that, a 2004 study showed that Taurine may decrease exercise induced DNA damage, as well as “enhance the capacity of exercise due to its cellular protective properties”. It’s unfortunate that Taurine has developed a sort of stigma because of its inclusion in energy drinks.

While Taurine does not provide “energy” in the way that caffeine does, several studies have shown its effectiveness as an antioxidant with exercise-enhancing properties. The mechanism of action here is relatively straight forward. It is widely believed that, while exercise fatigue generally results from a multitude of factors, oxidative stress contributes considerably. By decreasing oxidative stress as it occurs, Taurine may very well ward off fatigue. That’s not to say that you will last forever in the gym by supplementing with Taurine, but to most athletes, even one more rep is appreciated.

Caffeine

Caffeine is the most widely consumed psychoactive substance in the world, and is a well-established ergogenic aid. Caffeine consumption causes an increase in catecholamines (adrenaline, noradrenaline, and dopamine), which may raise the metabolic rate and/or promote fat oxidation. However, the weight loss effects of caffeine tend to fade with prolonged use, so it does not appear as though caffeine is an effective fat-burner in the long term. While caffeine’s weight loss potential is negligible, it increases focus and perceived energy in most people, which generally leads to more intense workouts (thus burning more fat), and may act as a mild appetite suppressant in some. Shred Her contains an undisclosed amount of caffeine, and it is unclear whether the green tea extract present in the formula also contains caffeine. Green Tea Extract is usually standardized for EGCG, but also contains caffeine unless decaffeinated.

Bitter Orange

The active ingredient found in Bitter Orange is known as Synephrine. Syneprhine gained popularity in the supplement community after the FDA banned Ephedra, due to its similar chemical structure. While Synephrine has been touted as a replacement for ephedra, it is important to understand that it is much less potent (which is why it is not banned also). However, that’s not to say it is useless. Preliminary studies indicate that Synephrine is able to raise metabolic rate and may induce lipolysis to some degree. While Synephrine itself has been around for almost 100 years, studies regarding its fat burning abilities are scarce and those that have been conducted generally combine synephrine with other stimulants such as caffeine. For that reason, it is difficult to examine the efficacy of the supplement for weight loss alone, but given the presence of caffeine in the formula syneprhine may very well contribute to weight loss.

Raspberry Ketone

Rasberry Ketone has become a popular weight-loss additive in dietary supplements, particularly those geared toward women. However, the evidence for raspberry ketone as a fat-burning ingredient is extremely limited and there is actually no direct evidence the ingredient is effective in oral, supplemental doses. In vitro studies using very high concentrations have shown positive results, but human studies are non-existent. The only human study that does exist grouped RK in with several other popular weight loss ingredients so the effects cannot be attributed to raspberry ketone. Even in rat studies, RK fail to show any significant fat-burning effects. The overall consensus of the scientific community is that raspberry ketone is nothing more than industry hype.

Ursolic Acid

Ursolic Acid, the primary active ingredient in Rosemary Leaf Extract, has been demonstrated to induce lipolysis in rat adipocites (fat cells) as well as preserve muscle mass in vitro. In mice, studies have shown decreased glucose levels in those given supplemental Ursolic acid. However, no current human studies exist upon which to draw conclusions. So far, it appears as though Ursolic Acid may be an effective “body re-composition” agent capable of reducing fat mass while preserving lean muscle mass but, given the current lack of human studies, we must view these findings as purely preliminary, and in need of human validation.

Guarana

Guarana is a plant native to the Amazon, the fruit of which contains caffeine. Although guarana is touted as being a sort of “slow-release” form of caffeine, a study published in the Journal of Pharmacy and Pharmacology showed that there was no difference in absorption rates in rats. Human studies have yet to be confirmed. In regards to weight loss, the efficacy of guarana for burning fat is limited to the caffeine content, and there is no evidence to suggest guarana has any additional benefit beyond the benefit of caffeine alone.

The Bottom Line

The Shred Her formula contains several effective weight loss ingredients, as well as some not-so-effective, over-hyped ingredients. Due to the presence of multiple stimulants, we would not suggest combining Shred Her with any other stimulant-containing products and would probably not take the supplement within several hours of bed time. As far as the “For Her” aspect of Shred Her, there is nothing in the formula that would make it better, or more effective, for women as opposed to men.

Still not sure which fat-burner is right for you? Take a look at our Top 10 Fat-Burners List!

REFERENCES
  1. Haaz, S., et al. “Citrus aurantium and synephrine alkaloids in the treatment of overweight and obesity: an update.” Obesity reviews 7.1 (2006): 79-88.
  2. Bempong, Daniel K., and Peter J. Houghton. “Dissolution and Absorption of Caffeine from Guarana.” Journal of Pharmacy and Pharmacology 44.9 (n.d.): 769-71.
  3. Lima, Waldecir P., et al. “Lipid metabolism in trained rats: Effect of guarana (< i> Paullinia cupana Mart.) supplementation.” Clinical Nutrition 24.6 (2005): 1019-1028.
  4. Li, Ying, et al. “Ursolic acid stimulates lipolysis in primary‐cultured rat adipocytes.” Molecular nutrition & food research 54.11 (2010): 1609-1617.
  5. Jang, Sun-Mi, et al. “Inhibitory effects of ursolic acid on hepatic polyol pathway and glucose production in streptozotocin-induced diabetic mice.” Metabolism59.4 (2010): 512-519.
  6. Vinson, Joe A., Bryan R. Burnham, and Mysore V. Nagendran. “Randomized, double-blind, placebo-controlled, linear dose, crossover study to evaluate the efficacy and safety of a green coffee bean extract in overweight subjects.”Diabetes, metabolic syndrome and obesity: targets and therapy 5 (2012): 21.
  7. Dellalibera, S. S. Ą., B. Lemaire, and S. Lafay. “„Svetol*, green coffee extract, induces weight loss and increases the lean to fat mass ratio in volunteers with overweight problem.”.” Phytotherapie 4.4 (2006): 194-197
  8. Ho, Lap, et al. “Dietary supplementation with decaffeinated green coffee improves diet-induced insulin resistance and brain energy metabolism in mice.”Nutritional neuroscience 15.1 (2012): 37-45.
  9. Arciero, PAUL J., et al. “Effects of caffeine ingestion on NE kinetics, fat oxidation, and energy expenditure in younger and older men.” American Journal of Physiology-Endocrinology And Metabolism 268.6 (1995): E1192-E1198.
  10. Silva, Luciano A., et al. “Taurine supplementation decreases oxidative stress in skeletal muscle after eccentric exercise.” Cell biochemistry and function 29.1 (2011): 43-49.
  11. Zhang, M., et al. “Role of taurine supplementation to prevent exercise-induced oxidative stress in healthy young men.” Amino acids 26.2 (2004): 203-207.

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