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Jack3d Micro Review

Jack3d Micro

 

Jack3d Micro is the sequel USP Labs’ original blockbuster pre-workout, Jack3d. Unlike the original Jack3d, Jack3d Micro contains no DMAA. It does contain some stimulants, as well as a few pump-inducing ingredients.

L-CITRULLINE:

L-Citrulline is finding its way into more and more workout supplements these days, so it seems like a no brainer for Jack3d to add to the mix if they are trying to play it safe. The benefits of Citrulline mostly pertain to ammonia removal and increasing nitric oxide. Ammonia builds up in exercising muscles eventually causing fatigue, so the removal of it may prevent muscle fatigue. Citrulline can also be converted into arginine, which may increase nitric oxide. This supplement is nothing special on its own, but may contribute to the overall effect. One thing that’s important to note as that most studies that have been done showing a positive correlation between citrulline supplementation and increased strength have used dosages far exceeding what could possibly be in jack3d’s proprietary blend. Still, there may be some benefit, especially when paired with Arginine Nitrate and Agmantine. The Jack3d Micro formula is more pump-based (nitric oxide) than stimulant-based.

ARGININE NITRATE:

Another form of arginine. However, this form has nitrate attached to it. Nitrate is converted by the body into Nitric Oxide. Nitrate supplementation has been shown to “lower oxygen demand during submaximal work”. Basically, it allows the muscles to more efficiently use oxygen. Again, nothing special on its own, but may contribute to the overall affect.

AGMATINE SULFATE:

Until recently, Agmantine was not widely used in the supplement industry. The proposed benefits for this include: Increased growth hormone production, anti-oxidant properties, increased nitric oxide, and fat loss. All of these seem like great reasons for jack3d to put it in their new formula, but since it is included with arginine and citrulline, we can assume that its in there for increasing NO. It’s worth mentioning that Agmatine has been shown to inhibit Nitric Oxide in Microglia (a type of glial cell located in the spinal cord and brain that are considered the first line of immune defense in the Central Nervous System). However, in the circulatory system, it has a different effect and supplementation has been shown to result in vasodilation by means of increased Nitric Oxide.

GRAPESEED EXTRACT:

The sought after ingredient in grape seed extract is resveratrol. Resveratrol is starting to become well known as a sort of “miracle” anti-oxidant. There have been no in vivo tests done to support these claims. However, in vitro studies show promise for free-radical scavenging properties. Still, we’re not really sure why they threw this in there. Seems a bit unnecessary.

CAFFEINE:

Caffeine is the most widely consumed psychoactive substance in the world, and is a well-established ergogenic aid. Caffeine consumption causes an increase in catecholamines (adrenaline, noradrenaline, and dopamine), which may raise the metabolic rate and/or promote fat oxidation. However, the weight loss effects of caffeine tend to fade with prolonged use, so it does not appear as though caffeine is a long-term effective fat burner. While caffeine’s weight loss potential is negligible, it increases focus and perceived energy in most people, which generally leads to more intense workouts (thus burning more fat), and may act as a mild appetite suppressant in some. Average doses of caffeine range from 70-200 mg. Jack3d Micro contains 125 mg of caffeine which, when combined with the other stimulants present in the formula, may provide users with increased focus and perceived energy.

NORCOCLAURINE:

The effects of Norococlaurine, also known as Higenamine, may pertain to fat-loss more than getting you pumped before your workout. However, the ingredient has stimulant properties that are reminiscent of ephedrine (though not nearly as potent). Norococlaurine has been demonstrated to act as a beta-2 adrenergic receptor agonist in rodents, in a similar way as Ephedrine. However, human studies are non-existent so it is impossible to say whether this effect is pertinent or substantial in humans. The animal studies have noted a short half-life (about 10 minutes in rabbits), which may mean any stimulant effects are short lived.

3,4 DIHYDROXYCINNAMIC ACID:

We’re not quite sure why USP included this in the stimulant blend. 3,4-Dihydroxcinnamic Acid, better known as Caffeic Acid, is not a stimulant at all. Rather, it is a potent (phenol) antioxidant. The company discusses the ingredient on their website but they fail to state why exactly is included in the formula. Infact, they claim that its been used as a sleeping aid in ancient times. One would wonder why this compound would be beneficial to working out, but we don’t see how it could be particularly harmful either.

THE BOTTOM LINE:

Jack3d Micro certainly has a better safety profile than the old Jack3d due to the exclusion of 1,3 Dimethylamylamine (DMAA). Although the safety profile has definitely been improved, it is missing the ingredient that was the corner stone of USP’s two best selling products Jack3d and Oxy Elite Pro. There is no doubt that DMAA was what set Jack3d apart from other pre workouts, so is it still worth it without it? That depends on the individual. USP claims they came out with Jack3d Micro because it represents a different type of pre-workout, but this is probably not the whole truth, but the FDA was clearly placing a lot of pressure on companies that were using DMAA in their supplements. In order to gain the benefit of the other ingredients, users of Jack3d Micro will likely have to consume more than one serving. Overall, Jack3d Micro just doesn’t jump out as a particularly impressive formula, though there is nothing terrible about it either.

REFERENCES
  1. Farney, Tyler M., Cameron G. Mccarthy, Robert E. Canale, Rick J. Allman, Jr., and Richard J. Bloomer. “Hemodynamic and Hematologic Profile of Healthy Adults Ingesting Dietary Supplements Containing 1,3-Dimethylamylamine and Caffeine.” Nutrition and Metabolic Insights (2012): 1-25.
  2. Hogervorst, Eef, Stephan Bandelow, Jeroen Schmitt, Roy Jentjens, Marta Oliveira, Judith Allgrove, Tom Carter, and Michael Gleeson. “Caffeine Improves Physical and Cognitive Performance during Exhaustive Exercise.” Medicine & Science in Sports & Exercise 40.10 (2008): 1841-851.
  3. “Journal of Applied Physiology”; Acute L-arginine Supplementation Reduces The O2 Cost of Moderate-intensity Exercise and Enhances High-intensity Exercise Tolerance; Stephen J. Bailey, et al.; November 2010
  4. Gulcin, I. “Antioxidant Activity of Caffeic Acid (3,4-dihydroxycinnamic Acid).” Toxicology217.2-3 (2006): 213-20.
  5. Larsen, F. J., E. Weitzberg, J. O. Lundberg, and B. Ekblom. “Effects of Dietary Nitrate on Oxygen Cost during Exercise.” Acta Physiologica 191.1 (2007): 59-66.
  6. Pérez-Guisado, Joaquín, and Philip M. Jakeman. “Citrulline Malate Enhances Athletic Anaerobic Performance and Relieves Muscle Soreness.” Journal of Strength and Conditioning Research 24.5 (2010): 1215-222.
  7. Bendahan, D., JP Mattei, B. Ghattas, S. Confort-Gouny, M. E. Le Guern, and PJ Cozzone. “Citrulline/malate Promotes Aerobic Energy Production in Human Exercising Muscle.” British Journal of Sports Medicine (2002)
  8. Abe, Kazuho, Yuzuru Abe, and Hiroshi Saito. “Agmatine Suppresses Nitric Oxide Production in Microglia.” Brain Research 872.1-2 (2000): 141-48.
  9. Gao, Yuqi, Bulent Gumusel, Gabor Koves, Anand Prasad, Qingzhong Hao, Albert Hyman, and Howard Lippton. “Agmatine: A Novel Endogenous Vasodilator Substance.” Life Sciences 57.8 (1995): PL83-L86.

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